U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 18:49:53 UTC 2021
Edited
by admin
on Sat Jun 26 18:49:53 UTC 2021
Protein Type RECEPTOR
Protein Sub Type TYROSINE KINASE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
4CH8636GFF
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
INSULIN RECEPTOR
Common Name English
INSR
Common Name English
INSULIN RECEPTOR SUBUNIT BETA
Common Name English
INSULIN RECEPTOR SUBUNIT ALPHA
Common Name English
CD220
Common Name English
Code System Code Type Description
UNIPROT
P06213
Created by admin on Sat Jun 26 18:49:54 UTC 2021 , Edited by admin on Sat Jun 26 18:49:54 UTC 2021
PRIMARY
WIKIPEDIA
INSULIN RECEPTOR
Created by admin on Sat Jun 26 18:49:54 UTC 2021 , Edited by admin on Sat Jun 26 18:49:54 UTC 2021
PRIMARY
FDA UNII
4CH8636GFF
Created by admin on Sat Jun 26 18:49:54 UTC 2021 , Edited by admin on Sat Jun 26 18:49:54 UTC 2021
PRIMARY
From To
1_8 1_26
1_126 1_155
1_159 1_182
1_169 1_188
1_192 1_201
1_196 1_207
1_208 1_216
1_212 1_225
1_228 1_237
1_241 1_253
1_259 1_284
1_266 1_274
1_288 1_301
1_304 1_308
1_312 1_333
1_435 1_468
1_647 2_137
2_63 2_72
1_524 3_524
3_8 3_26
3_126 3_155
3_159 3_182
3_169 3_188
3_192 3_201
3_196 3_207
3_208 3_216
3_212 3_225
3_228 3_237
3_241 3_253
3_259 3_284
3_266 3_274
3_288 3_301
3_304 3_308
3_312 3_333
3_435 3_468
3_647 4_137
4_63 4_72
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_16
N 1_25
N 1_78
N 1_111
N 1_215
N 1_255
N 1_295
N 1_337
N 1_397
N 1_418
N 1_514
N 1_606
N 1_624
N 1_671
N 2_7
N 2_20
N 2_158
N 2_171
N 3_16
N 3_25
N 3_78
N 3_111
N 3_215
N 3_255
N 3_295
N 3_337
N 3_397
N 3_418
N 3_514
N 3_606
N 3_624
N 3_671
N 4_7
N 4_20
N 4_158
N 4_171
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR
IC50
AGONIST -> TARGET
IGF-1 activates the insulin receptor at approximately 0.1x the potency of insulin.
AGONIST -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL