U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:18:14 GMT 2023
Edited
by admin
on Sat Dec 16 15:18:14 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
4B77GX0NA3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Barzolvolimab
USAN   INN  
Official Name English
Immunoglobulin G1 [233-alanine,234-glutamine,251-tyrosine,253-threonine,255-glutamic acid,321-glutamine,de-C-terminal-lysine], anti-(human receptor tyrosine kinase KIT extracellular domain) (human-Mus musculus monoclonal CDX-0159 γ1-chain), disulfide wi
Common Name English
barzolvolimab [INN]
Common Name English
CDX-0159
Code English
immunoglobulin G1-kappa, anti-[Homo sapiens KIT (KIT protooncogene receptor tyrosine kinase, c-kit, c-Kit, SCFR, CD117) extracellular domain], monoclonal antibody; gamma1 heavy chain (1-445) [VH Musmus/Homsap (Mus musculus IGHV1-76*01 (87.8%) -(IGHD) -IG
Common Name English
BARZOLVOLIMAB [USAN]
Common Name English
Code System Code Type Description
INN
11842
Created by admin on Sat Dec 16 15:18:14 GMT 2023 , Edited by admin on Sat Dec 16 15:18:14 GMT 2023
PRIMARY
CAS
2438203-51-9
Created by admin on Sat Dec 16 15:18:14 GMT 2023 , Edited by admin on Sat Dec 16 15:18:14 GMT 2023
PRIMARY
USAN
KL-133
Created by admin on Sat Dec 16 15:18:14 GMT 2023 , Edited by admin on Sat Dec 16 15:18:14 GMT 2023
PRIMARY
FDA UNII
4B77GX0NA3
Created by admin on Sat Dec 16 15:18:14 GMT 2023 , Edited by admin on Sat Dec 16 15:18:14 GMT 2023
PRIMARY
NCI_THESAURUS
C184860
Created by admin on Sat Dec 16 15:18:14 GMT 2023 , Edited by admin on Sat Dec 16 15:18:14 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
2_143 2_199
2_219 4_214
2_260 2_320
1_143 1_199
2_366 2_424
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_219 3_214
1_225 2_225
1_228 2_228
1_260 1_320
1_366 1_424
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_296
N 2_296
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL