LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A

Approval Year

Substance Class	Protein
Protein Type	ENZYME
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	4APO0P2BE7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A

Common Name

English

AOF2

Preferred Name

English

BRAF35-HDAC COMPLEX PROTEIN BHC110

Common Name

English

FLAVIN-CONTAINING AMINE OXIDASE DOMAIN-CONTAINING PROTEIN 2

Common Name

English

KIAA0601

Common Name

English

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Code System

Code

Type

Description

FDA UNII

4APO0P2BE7

PRIMARY

UNIPROT

O60341

PRIMARY

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Subunit 0

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Related Record

Type

Details


					LZ82JLT4UP

VAFIDEMSTAT

INHIBITOR -> TARGET


					XC0UT08SNJ

rel-trans-4-Amino-N-[(1R,2S)-2-phenylcyclopropyl]cyclohexanemethanamine

INHIBITOR -> TARGET


					12XU6D9FLM

INCB-059872

INHIBITOR -> TARGET

Interaction Type:

IRREVERSIBLE INHIBITOR

Amount:


					87ZW2258VM

T-914

INHIBITOR -> TARGET

Amount:

11 NANOMOLAR (average)


					W6F4FRQ5QC

PULRODEMSTAT

INHIBITOR -> TARGET

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Structural Modifications

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Modification Type	Location Site	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_135]	TYROSINE O-PHOSPHATE	2R86C98KDX
AMINO ACID SUBSTITUTION	[1_126] [1_131] [1_137] [1_166] [1_849]	DEXFOSFOSERINE	VI4F0K069V
AMINO ACID SUBSTITUTION	[1_59] [1_104]	THREONINE PHOSPHATE	3L4WX7B1EI

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL	ESTIMATED C4123H6532N1145O1281P8S24
MOL_WEIGHT	CHEMICAL

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