Rolistobart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 19:47:13 GMT 2023` Edited by `admin` on `Sat Dec 16 19:47:13 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Type	COMPLETE
Record UNII	49E3KB7L5M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Rolistobart

Official Name

English

Immunoglobulin G4-kappa, anti-[Homo sapiens LILRB4 (leukocyte immunoglobulin like receptor B4, ILT3, LIR-5, CD85k)], humanized monoclonal antibody (gamma4 heavy chain humanized (1-449) [VH (Homo sapiens IGHV3-7*01 (86.7%) -(IGHD) -IGHJ4*01(100%), CDR-IMG

Common Name

English

rolistobart [INN]

Common Name

English

Immunoglobulin G4 [230-proline], anti-(human leukocyte Ig-like receptor B4) (human-Mus musculus monoclonal A197U γ-4 chain), disulfide with human-Mus musculus monoclonal A197U κ-chain, dimer

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C199015

Created by admin on Sat Dec 16 19:47:13 GMT 2023 , Edited by admin on Sat Dec 16 19:47:13 GMT 2023

PRIMARY

INN

12567

Created by admin on Sat Dec 16 19:47:13 GMT 2023 , Edited by admin on Sat Dec 16 19:47:13 GMT 2023

PRIMARY

FDA UNII

49E3KB7L5M

Created by admin on Sat Dec 16 19:47:13 GMT 2023 , Edited by admin on Sat Dec 16 19:47:13 GMT 2023

PRIMARY

CAS

2723442-10-0

Created by admin on Sat Dec 16 19:47:13 GMT 2023 , Edited by admin on Sat Dec 16 19:47:13 GMT 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_136	4_218
2_149	2_205
2_263	2_323
1_136	3_218
2_369	2_427
3_23	3_92
3_138	3_198
4_23	4_92
4_138	4_198
1_149	1_205
1_228	2_228
1_231	2_231
1_263	1_323
1_369	1_427

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					D2EH4E7VJD

LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 4

TARGET->LIGAND

Amount:

Related Record Type Details


					49E3KB7L5M

Rolistobart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL