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Details

Stereochemistry ACHIRAL
Molecular Formula C16H13N3O6
Molecular Weight 343.2909
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of IPSALAZIDE

SMILES

OC(=O)CNC(=O)C1=CC=C(C=C1)\N=N\C2=CC=C(O)C(=C2)C(O)=O

InChI

InChIKey=CQSRTOJJBONKMC-VHEBQXMUSA-N
InChI=1S/C16H13N3O6/c20-13-6-5-11(7-12(13)16(24)25)19-18-10-3-1-9(2-4-10)15(23)17-8-14(21)22/h1-7,20H,8H2,(H,17,23)(H,21,22)(H,24,25)/b19-18+

HIDE SMILES / InChI

Molecular Formula C16H13N3O6
Molecular Weight 343.2909
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

IPSALAZIDE is a sulfasalazine analog designed as a colon-specific delivery system for the treatment of inflammatory bowel disease by releasing 5-aminosalicylic acid in the gastrointestinal tract.

Approval Year

PubMed

PubMed

TitleDatePubMed
Studies of two novel sulfasalazine analogs, ipsalazide and balsalazide.
1983 Jul
Clinical pharmacokinetics of sulphasalazine, its metabolites and other prodrugs of 5-aminosalicylic acid.
1985 Jul-Aug
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 16:28:59 GMT 2023
Edited
by admin
on Fri Dec 15 16:28:59 GMT 2023
Record UNII
499H4332KZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IPSALAZIDE
INN   MART.  
INN  
Official Name English
IPSALAZIDE [MART.]
Common Name English
BX-650A
Code English
BX 650 A
Code English
BX-650 A
Code English
ipsalazide [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C257
Created by admin on Fri Dec 15 16:28:59 GMT 2023 , Edited by admin on Fri Dec 15 16:28:59 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C73087
Created by admin on Fri Dec 15 16:28:59 GMT 2023 , Edited by admin on Fri Dec 15 16:28:59 GMT 2023
PRIMARY
INN
5222
Created by admin on Fri Dec 15 16:28:59 GMT 2023 , Edited by admin on Fri Dec 15 16:28:59 GMT 2023
PRIMARY
EVMPD
SUB08289MIG
Created by admin on Fri Dec 15 16:28:59 GMT 2023 , Edited by admin on Fri Dec 15 16:28:59 GMT 2023
PRIMARY
SMS_ID
100000083128
Created by admin on Fri Dec 15 16:28:59 GMT 2023 , Edited by admin on Fri Dec 15 16:28:59 GMT 2023
PRIMARY
PUBCHEM
9571082
Created by admin on Fri Dec 15 16:28:59 GMT 2023 , Edited by admin on Fri Dec 15 16:28:59 GMT 2023
PRIMARY
CAS
80573-03-1
Created by admin on Fri Dec 15 16:28:59 GMT 2023 , Edited by admin on Fri Dec 15 16:28:59 GMT 2023
PRIMARY
ChEMBL
CHEMBL2104872
Created by admin on Fri Dec 15 16:28:59 GMT 2023 , Edited by admin on Fri Dec 15 16:28:59 GMT 2023
PRIMARY
FDA UNII
499H4332KZ
Created by admin on Fri Dec 15 16:28:59 GMT 2023 , Edited by admin on Fri Dec 15 16:28:59 GMT 2023
PRIMARY
MESH
C038636
Created by admin on Fri Dec 15 16:28:59 GMT 2023 , Edited by admin on Fri Dec 15 16:28:59 GMT 2023
PRIMARY
Related Record Type Details
METABOLIC ENZYME -> SUBSTRATE
Related Record Type Details
METABOLITE -> PARENT
AMOUNT ADMINISTERED
URINE
METABOLITE ACTIVE -> PRODRUG
METABOLITE -> PARENT
AMOUNT ADMINISTERED
FECAL