IPSALAZIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H13N3O6
Molecular Weight	343.2909
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CNC(=O)C1=CC=C(C=C1)\N=N\C2=CC(C(O)=O)=C(O)C=C2

InChI

InChIKey=CQSRTOJJBONKMC-VHEBQXMUSA-N

InChI=1S/C16H13N3O6/c20-13-6-5-11(7-12(13)16(24)25)19-18-10-3-1-9(2-4-10)15(23)17-8-14(21)22/h1-7,20H,8H2,(H,17,23)(H,21,22)(H,24,25)/b19-18+

HIDE SMILES / InChI

Molecular Formula	C16H13N3O6
Molecular Weight	343.2909
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/mesh/67038636 | https://www.ncbi.nlm.nih.gov/pubmed/6345112

IPSALAZIDE is a sulfasalazine analog designed as a colon-specific delivery system for the treatment of inflammatory bowel disease by releasing 5-aminosalicylic acid in the gastrointestinal tract.

Originator

Approval Year

PubMed

Title	Date	PubMed
Novel oral colon-specific drug delivery systems for pharmacotherapy of peptide and nonpeptide drugs.	1999-07	12973398
Clinical pharmacokinetics of sulphasalazine, its metabolites and other prodrugs of 5-aminosalicylic acid.	1985-07-01	2864155
Studies of two novel sulfasalazine analogs, ipsalazide and balsalazide.	1983-07	6345112

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:29:13 GMT 2025` Edited by `admin` on `Mon Mar 31 18:29:13 GMT 2025`
Record UNII	499H4332KZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IPSALAZIDE

Official Name

English

BX 650 A

Preferred Name

English

IPSALAZIDE [MART.]

Common Name

English

BX-650A

Code

English

BX-650 A

Code

English

ipsalazide [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257