2,6-DI-TERT-BUTYL-4-METHYLENE-2,5-CYCLOHEXADIENONE

CC(C)(C)C1=CC(=C)C=C(C1=O)C(C)(C)C

InChIKey=JJQCWPWUHZFKBN-UHFFFAOYSA-N

InChI=1S/C15H22O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9H,1H2,2-7H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Carbonyl reductase inactivation may contribute to mouse lung tumor promotion by electrophilic metabolites of butylated hydroxytoluene: protein alkylation in vivo and in vitro.	2008-08	18597497
Immunochemical and proteomic analysis of covalent adducts formed by quinone methide tumor promoters in mouse lung epithelial cell lines.	2005-10	16533022
Inhibition of glutathione S-transferase P1-1 in mouse lung epithelial cells by the tumor promoter 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone (BHT-quinone methide): protein adducts investigated by electrospray mass spectrometry.	2004-12	15606144
Responses of tumorigenic and non-tumorigenic mouse lung epithelial cell lines to electrophilic metabolites of the tumor promoter butylated hydroxytoluene.	2003-03-06	12606153

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:10:05 GMT 2025` Edited by `admin` on `Mon Mar 31 19:10:05 GMT 2025`
Record UNII	49860VI52B
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

2,5-CCYCLOHEXADIEN-1-ONE, 2,6-BIS(1,1-DIMETHYLETHYL)-4- METHYLENE-

Preferred Name

English

2,6-DI-TERT-BUTYL-4-METHYLENE-2,5-CYCLOHEXADIENONE

Systematic Name

English

BHT-QUINONE METHIDE

Common Name

English

2,6-BIS(1,1-DIMETHYLETHYL)-4-METHYLENE-2,5-CYCLOHEXADIEN-1- ONE

Systematic Name

English

2,6-DI-T-BUTYL-4-METHYLENE-2,5-CYCLOHEXADIENONE

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID70180707