2,6-DI-TERT-BUTYL-4-METHYLENE-2,5-CYCLOHEXADIENONE

CC(C)(C)C1=CC(=C)C=C(C1=O)C(C)(C)C

InChIKey=JJQCWPWUHZFKBN-UHFFFAOYSA-N

InChI=1S/C15H22O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9H,1H2,2-7H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Responses of tumorigenic and non-tumorigenic mouse lung epithelial cell lines to electrophilic metabolites of the tumor promoter butylated hydroxytoluene.	2003 Mar 6	12606153
Inhibition of glutathione S-transferase P1-1 in mouse lung epithelial cells by the tumor promoter 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone (BHT-quinone methide): protein adducts investigated by electrospray mass spectrometry.	2004 Dec	15606144
Immunochemical and proteomic analysis of covalent adducts formed by quinone methide tumor promoters in mouse lung epithelial cell lines.	2005 Oct	16533022
Carbonyl reductase inactivation may contribute to mouse lung tumor promotion by electrophilic metabolites of butylated hydroxytoluene: protein alkylation in vivo and in vitro.	2008 Aug	18597497

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:18:25 GMT 2023` Edited by `admin` on `Fri Dec 15 18:18:25 GMT 2023`
Record UNII	49860VI52B
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

2,6-DI-TERT-BUTYL-4-METHYLENE-2,5-CYCLOHEXADIENONE

Systematic Name

English

BHT-QUINONE METHIDE

Common Name

English

2,5-CCYCLOHEXADIEN-1-ONE, 2,6-BIS(1,1-DIMETHYLETHYL)-4- METHYLENE-

Common Name

English

2,6-BIS(1,1-DIMETHYLETHYL)-4-METHYLENE-2,5-CYCLOHEXADIEN-1- ONE

Systematic Name

English

2,6-DI-T-BUTYL-4-METHYLENE-2,5-CYCLOHEXADIENONE

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID70180707