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Details

Stereochemistry ABSOLUTE
Molecular Formula 2C4H6O4S2.OTc
Molecular Weight 479.342
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 3

SHOW SMILES / InChI
Structure of TECHNETIUM TC-99M SUCCIMER

SMILES

O=[99Tc+3].OC(=O)[C@@H](S)[C@@H](S)C(O)=O.OC(=O)[C@@H](S)[C@@H](S)C(O)=O

InChI

InChIKey=VKIPEVJBUHKZRV-RSQQSNPGSA-N
InChI=1S/2C4H6O4S2.O.Tc/c2*5-3(6)1(9)2(10)4(7)8;;/h2*1-2,9-10H,(H,5,6)(H,7,8);;/q;;;+3/t2*1-,2+;;/i;;;1+1

HIDE SMILES / InChI
Molecular Formula C4H5O4S2
Molecular Weight 181.21
Charge -1
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula OTc
Molecular Weight 114.9057
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

1973
98
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Approved
8429
OSTEOLITE

Approved Use

Unknown

Launch Date

1977
Diagnostic
Approved
8429
DRAXIMAGE MDP-10

Approved Use

MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis.

Launch Date

1978
PubMed

PubMed

TitleDatePubMed
Future of low specific activity molybdenum-99/technetium-99m generator.
2012 Oct
Patents

Patents

20050082469
43

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:49:28 GMT 2023
Edited
by admin
on Fri Dec 15 15:49:28 GMT 2023
Record UNII
494JNQ8L28
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TECHNETIUM TC-99M SUCCIMER
Common Name English
TECHNETIUM (99MTC) PENTAVALENT SUCCIMER
Common Name English
TECHNETIUM-99M-(V)-DIMERCAPTOSUCCINIC ACID
Common Name English
NEPHROSCAN
Brand Name English
TECHNETIUM-99-DMSA
Common Name English
TECHNETIUM TC-99M SUCCIMER KIT
ORANGE BOOK  
Common Name English
TECHNETIUM TC 99M SUCCIMER
USP   WHO-DD  
Common Name English
TECHNETIUM-99 DIMERCAPTOSUCCINATE
Common Name English
99MTC-DMSA
Common Name English
TECHNETIUM TC 99M SUCCIMER [USP IMPURITY]
Common Name English
TC-99M DMSA
Common Name English
BUTANEDIOIC ACID, 2,3-DIMERCAPTO-, TECHNETIUM-99TC SALT
Common Name English
PENTAVALENT TECHNETIUM-99M-DIMERCAPTOSUCCINIC
Common Name English
TECHNETIUM (SUP 99M)TC) DIMERCAPTOSUCCINIC ACID
Common Name English
TECHNETIUM TC 99M DIMERCAPTOSUCCINIC ACID
Common Name English
TECHNETIUM TC-99M SUCCIMER KIT [ORANGE BOOK]
Common Name English
Technetium tc 99m succimer [WHO-DD]
Common Name English
Classification Tree Code System Code
WHO-ATC V09IA03
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
NDF-RT N0000000205
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
WHO-ATC V09CA02
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
NDF-RT N0000177914
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
NCI_THESAURUS C2124
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
WHO-VATC QV09CA02
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
Code System Code Type Description
LACTMED
Technetium Tc 99m Dimercaptosuccinic Acid
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
PRIMARY
EVMPD
SUB127165
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
ALTERNATIVE
ChEMBL
CHEMBL2110572
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
PRIMARY
EVMPD
SUB12355MIG
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
PRIMARY
FDA UNII
494JNQ8L28
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
PRIMARY
PUBCHEM
134694302
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
PRIMARY
CAS
205510-15-2
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
ALTERNATIVE
NCI_THESAURUS
C87408
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
PRIMARY
CAS
65438-08-6
Created by admin on Fri Dec 15 15:49:28 GMT 2023 , Edited by admin on Fri Dec 15 15:49:28 GMT 2023
PRIMARY
Related Record Type Details
Structure of SUCCIMER
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of TECHNETIUM TC-99M SUCCIMER
ACTIVE MOIETY
Structure of TECHNETIUM TC-99M
ACTIVE MOIETY
NIH
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