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Details

Stereochemistry ACHIRAL
Molecular Formula 3C6H4NO2.Fe
Molecular Weight 422.149
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERRIC PICOLINATE

SMILES

[Fe+3].[O-]C(=O)C1=CC=CC=N1.[O-]C(=O)C2=CC=CC=N2.[O-]C(=O)C3=CC=CC=N3

InChI

InChIKey=XYLIUBFEJNAWSC-UHFFFAOYSA-K
InChI=1S/3C6H5NO2.Fe/c3*8-6(9)5-3-1-2-4-7-5;/h3*1-4H,(H,8,9);/q;;;+3/p-3

HIDE SMILES / InChI

Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C6H4NO2
Molecular Weight 122.1015
Charge -1
Count
MOL RATIO 3 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Ferric picolinate and ferric acetohydroxamate are effective anti-biofilm compounds against both lab and clinical strains of P. aeruginosa and are readily nebulized into particles of suitable size for lung delivery.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
80.0 µM [IC50]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Ferric picolinate (50-500 umol/l) inhibited Pseudomonas aeruginosa biofilms. As iron (Ferric picolinate) concentration increased, Pseudomonas aeruginosa biofilm increased from 0 to 50 umol/l, when the trend reversed and the biofilms of P. aeruginosa PA14 were powerfully disrupted, with IC50 80 umol/l.
Substance Class Chemical
Record UNII
48VAK352CN
Record Status Validated (UNII)
Record Version