Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H8ClN5 |
| Molecular Weight | 221.646 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=NC=NC(NC2=CC=C(Cl)C=C2)=N1
InChI
InChIKey=YRZQHIVOIFJEEE-UHFFFAOYSA-N
InChI=1S/C9H8ClN5/c10-6-1-3-7(4-2-6)14-9-13-5-12-8(11)15-9/h1-5H,(H3,11,12,13,14,15)
| Molecular Formula | C9H8ClN5 |
| Molecular Weight | 221.646 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Chlorazanil is a triazine derivative and diuretic agent. Chlorazanil appears to prevent the absorption of sodium and chloride in the distal convoluted tubule. As nonmercurial orally effective diuretic agent, Chlorazanil is prohibited in sport according to the regulations of the World Anti-Doping Agency (WADA).
Approval Year
Sample Use Guides
In conscious unloaded Sprague-Dawley female rats chlorazanil (10 mg/kg orally) markedly increased urinary prostaglandin E2-excretion from 51 +/- 9 to 813 +/- 112 ng/kg/6 hrs. Urinary flow rate increased from 12.8 +/- 0.6 to 42.0 +/- 1.4 ml/kg/6 hrs and urinary sodium excretion from 0.96 +/- 0.12 to 3.86 +/- 0.33 mmol/kg/6 hrs. Urinary potassium excretion was unchanged.
Route of Administration:
Oral
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:12:29 GMT 2023
by
admin
on
Fri Dec 15 16:12:29 GMT 2023
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| Record UNII |
48SN4K3W0E
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| Record Status |
Validated (UNII)
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C448
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724
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10374
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C017837
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500-42-5
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C79796
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591
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100000081558
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SALT/SOLVATE -> PARENT |
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ACTIVE MOIETY |
