RELOXALIASE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 20:44:07 GMT 2025` Edited by `admin` on `Tue Apr 01 20:44:07 GMT 2025`
Protein Type	ENZYME
Protein Sub Type	OXALATE DECARBOXYLASE
Sequence Origin	BACTERIAL
Sequence Type	COMPLETE
Record UNII	48OB405WWC
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ALLN-177

Preferred Name

English

RELOXALIASE

Official Name

English

reloxaliase [INN]

Common Name

English

OXALATE DECARBOXYLASE (BACILLUS SUBTILIS (STRAIN 168))

Common Name

English

Reloxaliase [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29726

Created by admin on Tue Apr 01 20:44:07 GMT 2025 , Edited by admin on Tue Apr 01 20:44:07 GMT 2025

FDA ORPHAN DRUG

508015

Created by admin on Tue Apr 01 20:44:07 GMT 2025 , Edited by admin on Tue Apr 01 20:44:07 GMT 2025

FDA ORPHAN DRUG

578917

Created by admin on Tue Apr 01 20:44:07 GMT 2025 , Edited by admin on Tue Apr 01 20:44:07 GMT 2025

Code System Code Type Description

FDA UNII

48OB405WWC

Created by admin on Tue Apr 01 20:44:07 GMT 2025 , Edited by admin on Tue Apr 01 20:44:07 GMT 2025

PRIMARY

NCI_THESAURUS

C152180

Created by admin on Tue Apr 01 20:44:07 GMT 2025 , Edited by admin on Tue Apr 01 20:44:07 GMT 2025

PRIMARY

DRUG BANK

DB15560

Created by admin on Tue Apr 01 20:44:07 GMT 2025 , Edited by admin on Tue Apr 01 20:44:07 GMT 2025

PRIMARY

UNIPROT

O34714

Created by admin on Tue Apr 01 20:44:07 GMT 2025 , Edited by admin on Tue Apr 01 20:44:07 GMT 2025

PRIMARY

INN

10493

Created by admin on Tue Apr 01 20:44:07 GMT 2025 , Edited by admin on Tue Apr 01 20:44:07 GMT 2025

PRIMARY

SMS_ID

100000177293

Created by admin on Tue Apr 01 20:44:07 GMT 2025 , Edited by admin on Tue Apr 01 20:44:07 GMT 2025

PRIMARY

CAS

202011-67-4

Created by admin on Tue Apr 01 20:44:07 GMT 2025 , Edited by admin on Tue Apr 01 20:44:07 GMT 2025

PRIMARY

CAS

9024-97-9

Created by admin on Tue Apr 01 20:44:07 GMT 2025 , Edited by admin on Tue Apr 01 20:44:07 GMT 2025

GENERIC (FAMILY)

Linkage Type	Residue Index
COORDINATION COMPOUND	2_273	2_275	2_280	2_319
COORDINATION COMPOUND	6_273	6_275	6_280	6_319
COORDINATION COMPOUND	3_273	3_275	3_280	3_319
COORDINATION COMPOUND	5_95	5_97	5_101	5_140
COORDINATION COMPOUND	2_95	2_97	2_101	2_140
COORDINATION COMPOUND	6_95	6_97	6_101	6_140
COORDINATION COMPOUND	5_273	5_275	5_280	5_319
COORDINATION COMPOUND	4_273	4_275	4_280	4_319
COORDINATION COMPOUND	3_95	3_97	3_101	3_140
COORDINATION COMPOUND	1_273	1_275	1_280	1_319
COORDINATION COMPOUND	4_95	4_97	4_101	4_140
COORDINATION COMPOUND	1_95	1_97	1_101	1_140

Related Record Type Details


					9E7R5L6H31

SUBSTRATE -> METABOLIC ENZYME

Amount:

Related Record Type Details


					48OB405WWC

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[3_95] [3_97] [3_101] [3_140]	SITE_SPECIFIC			MANGANESE BINDING HHHE-TYPE	DH68G9JC6Y
AMINO_ACID_SUBSTITUTION	[2_273] [2_275] [2_280] [2_319]	SITE_SPECIFIC			MANGANESE BINDING HHHE-TYPE	DH68G9JC6Y
AMINO_ACID_SUBSTITUTION	[4_95] [4_97] [4_101] [4_140]	SITE_SPECIFIC			MANGANESE BINDING HHHE-TYPE	DH68G9JC6Y
AMINO_ACID_SUBSTITUTION	[1_273] [1_275] [1_280] [1_319]	SITE_SPECIFIC			MANGANESE BINDING HHHE-TYPE	DH68G9JC6Y
AMINO_ACID_SUBSTITUTION	[1_95] [1_97] [1_101] [1_140]	SITE_SPECIFIC			MANGANESE BINDING HHHE-TYPE	DH68G9JC6Y
AMINO_ACID_SUBSTITUTION	[2_95] [2_97] [2_101] [2_140]	SITE_SPECIFIC			MANGANESE BINDING HHHE-TYPE	DH68G9JC6Y
AMINO_ACID_SUBSTITUTION	[6_273] [6_275] [6_280] [6_319]	SITE_SPECIFIC			MANGANESE BINDING HHHE-TYPE	DH68G9JC6Y
AMINO_ACID_SUBSTITUTION	[6_95] [6_97] [6_101] [6_140]	SITE_SPECIFIC			MANGANESE BINDING HHHE-TYPE	DH68G9JC6Y
AMINO_ACID_SUBSTITUTION	[4_273] [4_275] [4_280] [4_319]	SITE_SPECIFIC			MANGANESE BINDING HHHE-TYPE	DH68G9JC6Y
AMINO_ACID_SUBSTITUTION	[5_95] [5_97] [5_101] [5_140]	SITE_SPECIFIC			MANGANESE BINDING HHHE-TYPE	DH68G9JC6Y
AMINO_ACID_SUBSTITUTION	[5_273] [5_275] [5_280] [5_319]	SITE_SPECIFIC			MANGANESE BINDING HHHE-TYPE	DH68G9JC6Y
AMINO_ACID_SUBSTITUTION	[3_273] [3_275] [3_280] [3_319]	SITE_SPECIFIC			MANGANESE BINDING HHHE-TYPE	DH68G9JC6Y

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL