BMS-181321

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H25N7O4.OTc.H
Molecular Weight	495.3278
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	2
Charge	0
Stereo Comments	J Med Chem, 37, 9-17 (1994), https://pubs.acs.org/doi/pdf/10.1021/jm00027a002

SHOW SMILES / InChI

Structure Search

SMILES

[H+].O=[99Tc+3].C\C(=N/[O-])C(C)(C)[N-]CCC[N-]C(C)(C)C(\CN1C=CN=C1[N+]([O-])=O)=N\[O-]

InChI

InChIKey=BACDTMMAFRHWHW-KTZCKAEQSA-M

InChI=1S/C16H27N7O4.O.Tc/c1-12(20-24)15(2,3)18-7-6-8-19-16(4,5)13(21-25)11-22-10-9-17-14(22)23(26)27;;/h9-10,24-25H,6-8,11H2,1-5H3;;/q-2;;+3/p-1/b20-12+,21-13+;;/i;;1+1

HIDE SMILES / InChI

Molecular Formula	OTc
Molecular Weight	114.9057
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C16H27N7O4
Molecular Weight	381.4301
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry
Defined Stereocenters	0 / 0
E/Z Centers	2
Optical Activity	NONE

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2596
bone problems 40 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8583	OSTEOLITE Approved Use Unknown Launch Date 1977
osteogenesis 40 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8583	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 1978

PubMed

Title	Date	PubMed
Future of low specific activity molybdenum-99/technetium-99m generator.	2012-10	22642420

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:36:36 GMT 2025` Edited by `admin` on `Mon Mar 31 22:36:36 GMT 2025`
Record UNII	48JMI4M3B3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TECHNETATE(1-)-99MTC, (3-((3-((2-(HYDROXYIMINO)-1,1-DIMETHYLPROPYL)AMINO)PROPYL)AMINO)-3-METHYL-1-(2-NITRO-1H-IMIDAZOL-1-YL)-2-BUTANONE OXIMATO(4-)-N2,N3,N3',N3'')OXO-, HYDROGEN, (SP-5-15)-

Preferred Name

English

BMS-181321

Common Name

English

Code System Code Type Description

PUBCHEM

9577288

Created by admin on Mon Mar 31 22:36:36 GMT 2025 , Edited by admin on Mon Mar 31 22:36:36 GMT 2025

PRIMARY

CAS

149447-21-2

Created by admin on Mon Mar 31 22:36:36 GMT 2025 , Edited by admin on Mon Mar 31 22:36:36 GMT 2025

PRIMARY

FDA UNII

48JMI4M3B3

Created by admin on Mon Mar 31 22:36:36 GMT 2025 , Edited by admin on Mon Mar 31 22:36:36 GMT 2025

PRIMARY

Related Record Type Details


					6EW75241VU

TECHNETIUM TC-99M

ACTIVE MOIETY

Details

SMILES

InChI

Approval Year

Conditions

Approved Use

Launch Date

Approved Use

Launch Date

PubMed

Patents

Sample Use Guides