BISPYRITHIONE MAGSULFEX

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H8N2O2S2.Mg.O4S.3H2O
Molecular Weight	426.726
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O.O.O.[Mg++].[O-]S([O-])(=O)=O.[O-][N+]1=CC=CC=C1SSC2=[N+]([O-])C=CC=C2

InChI

InChIKey=FNJVKRQYEQVPLK-UHFFFAOYSA-L

InChI=1S/C10H8N2O2S2.Mg.H2O4S.3H2O/c13-11-7-3-1-5-9(11)15-16-10-6-2-4-8-12(10)14;;1-5(2,3)4;;;/h1-8H;;(H2,1,2,3,4);3*1H2/q;+2;;;;/p-2

HIDE SMILES / InChI

Molecular Formula	H2O4S
Molecular Weight	98.078
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C10H8N2O2S2
Molecular Weight	252.313
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Mg
Molecular Weight	24.305
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://medikamio.com/fr-ch/medicaments/crimanex-shampoo/pil

Dipyrithione is a pyrithione derivate used as bactericide and fungicide. The drug was marketed under the name Crimanex in the form of shampoo for the treatment of dandruff, however it is no longer available on the manufacturer website (Drossa Pharm).

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Dandruff 7 Sources: https://medikamio.com/fr-ch/medicaments/crimanex-shampoo/pil	Curative		Approved 8583	CRIMANEX Approved Use To treat dandruff.

Doses

Dose	Population	Adverse events
400 mg/m2 single, topical Highest studied dose Dose: 400 mg/m2 Route: topical Route: single Dose: 400 mg/m2 Sources: https://pubmed.ncbi.nlm.nih.gov/898185/	healthy, ADULT Health Status: healthy Age Group: ADULT Sex: M Food Status: UNKNOWN Sources: https://pubmed.ncbi.nlm.nih.gov/898185/	Sources: https://pubmed.ncbi.nlm.nih.gov/898185/

PubMed

Title	Date	PubMed
New finding of an anti-TB compound in the genus Marsypopetalum (Annonaceae) from a traditional herbal remedy of Laos.	2014-02-03	24333958
Toxicity of metal pyrithione photodegradation products to marine organisms with indirect evidence for their presence in seawater.	2010-05	19967345
Bioactive pyridine-N-oxide disulfides from Allium stipitatum.	2009-03-27	19093848

Patents

Sample Use Guides

In Vivo Use Guide

To wash you head with the shampoo 1 or 2 times per week.

Route of Administration: Topical

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:03:01 GMT 2025` Edited by `admin` on `Mon Mar 31 18:03:01 GMT 2025`
Record UNII	48H0YX0NT4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

OMADINE MDS

Preferred Name

English

BISPYRITHIONE MAGSULFEX

Official Name

English

MAGNESIUM, (2,2'-DITHIOBIS(PYRIDINE) 1,1'-DIOXIDE-O,O',S)(SULFATO(2-)-O)-, TRIHYDRATE, (T-4)-

Common Name

English

BISPYRITHIONE MAGSULFEX [USAN]

Common Name

English

(2,2'-DITHIODIPYRIDINE 1,1'-DIOXIDE)SULFATOMAGNESIUM TRIHYDRATE

Common Name

English

DIPYRITHIONE MAGNESIUM SULFATE TRIHYDRATE

Common Name

English

BISPYRITHIONE MAGSULFEX TRIHYDRATE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C254