Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C21H33N3O5S.ClH |
Molecular Weight | 476.03 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 3 / 3 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2N=CN3CCCCCC3)C(=O)OCOC(=O)C(C)(C)C
InChI
InChIKey=UHPXMYLONAGUPC-YKBWBZKYSA-N
InChI=1S/C21H33N3O5S.ClH/c1-20(2,3)19(27)29-13-28-18(26)15-21(4,5)30-17-14(16(25)24(15)17)22-12-23-10-8-6-7-9-11-23;/h12,14-15,17H,6-11,13H2,1-5H3;1H/b22-12+;/t14-,15+,17-;/m1./s1
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C21H33N3O5S |
Molecular Weight | 439.569 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 3 / 3 |
E/Z Centers | 1 |
Optical Activity | UNSPECIFIED |
DescriptionSources: http://www.drugbank.ca/drugs/DB01163Curator's Comment: Description was created based on several sources, including
http://www.mims.com/india/drug/info/mecillinam?type=full&mtype=generic and https://www.ncbi.nlm.nih.gov/pubmed/3885172
Sources: http://www.drugbank.ca/drugs/DB01163
Curator's Comment: Description was created based on several sources, including
http://www.mims.com/india/drug/info/mecillinam?type=full&mtype=generic and https://www.ncbi.nlm.nih.gov/pubmed/3885172
Amdinocillin is a novel, semisynthetic penicillin effective against many gram-negative bacteria. The antibacterial activity of amdinocillin is derived from its ability to bind specifically and avidly to Penicillin Binding Protein-2 (PBP 2). Amdinocillin is active alone against many gram-negative organisms. Pseudomonas and non-fermenting gram-negative bacteria, however, are usually resistant. Amdinocillin, in combination with many beta-lactams, exhibits marked synergy against many enterobacteriaceae. No such synergy can be demonstrated for gram-positive organisms or pseudomonas species. Amdinocillin is not beta-lactamase stable. Organisms which produce high levels of plasma-mediated beta-lactamase are resistant to the drug. Used in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species. Used mainly against Gram negative organisms. Amdinocillin is not available in the United States.
CNS Activity
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6274562
Curator's Comment: Poor penetration in humans
Originator
Sources: https://www.ncbi.nlm.nih.gov/pubmed/232703
Curator's Comment: Mecillinam (Amdinocillin) developed by Leo Pharmaceuticals Balleherup, Denmark),
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: Q8DR59 Gene ID: 934791.0 Gene Symbol: pbpA Target Organism: Streptococcus pneumoniae (strain ATCC BAA-255 / R6) Sources: https://www.ncbi.nlm.nih.gov/pubmed/25845878 |
0.224 µM [IC50] | ||
Target ID: UniProtKB - Q7CRA4, pbp1b, Streptococcus pneumoniae Sources: https://www.ncbi.nlm.nih.gov/pubmed/25845878 |
0.147 µM [IC50] | ||
Target ID: UniProtKB - Q8DNB6, pbp2a, Streptococcus pneumoniae Sources: https://www.ncbi.nlm.nih.gov/pubmed/7447421 |
30.0 nM [IC50] | ||
Target ID: UniProtKB - A0A0E9DY48, PBP1, Chlamydia trachomatis Sources: https://www.ncbi.nlm.nih.gov/pubmed/11120983 |
0.6 nM [IC50] | ||
Target ID: UniProtKB - L0BBN1, pbp3, Haemophilus influenzae Sources: https://www.ncbi.nlm.nih.gov/pubmed/6972731 |
3.7 nM [IC50] | ||
Target ID: P0AD65 Gene ID: 945240.0 Gene Symbol: mrdA Target Organism: Escherichia coli (strain K12) Sources: https://www.ncbi.nlm.nih.gov/pubmed/25733506 |
0.06 nM [IC50] |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Curative | Mecillinam Approved UseUrinary tract infections Launch Date4.72348787E11 |
Cmax
Value | Dose | Co-administered | Analyte | Population |
---|---|---|---|---|
87.3 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6311087/ |
15 mg/kg bw single, intravenous dose: 15 mg/kg bw route of administration: Intravenous experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
4.3 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/3377469/ |
400 mg single, oral dose: 400 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FED |
|
3.2 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/3377469/ |
400 mg single, oral dose: 400 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
3.6 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/3377469/ |
400 mg single, oral dose: 400 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
4.1 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/3377469/ |
400 mg single, oral dose: 400 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FED |
|
49.5 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6282208/ |
10 mg/kg bw 6 times / day steady-state, intravenous dose: 10 mg/kg bw route of administration: Intravenous experiment type: STEADY-STATE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
26.2 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6311087/ |
10 mg/kg bw single, intramuscular dose: 10 mg/kg bw route of administration: Intramuscular experiment type: SINGLE co-administered: |
AMDINOCILLIN serum | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
29.6 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6311087/ |
15 mg/kg bw single, intramuscular dose: 15 mg/kg bw route of administration: Intramuscular experiment type: SINGLE co-administered: |
AMDINOCILLIN serum | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
49.4 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6311087/ |
10 mg/kg bw single, intravenous dose: 10 mg/kg bw route of administration: Intravenous experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
AUC
Value | Dose | Co-administered | Analyte | Population |
---|---|---|---|---|
112.97 μg × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6311087/ |
15 mg/kg bw single, intravenous dose: 15 mg/kg bw route of administration: Intravenous experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
10 μg × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/3377469/ |
400 mg single, oral dose: 400 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FED |
|
7.7 μg × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/3377469/ |
400 mg single, oral dose: 400 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
8.1 μg × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/3377469/ |
400 mg single, oral dose: 400 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
9.7 μg × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/3377469/ |
400 mg single, oral dose: 400 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FED |
|
47.94 μg × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6311087/ |
10 mg/kg bw single, intramuscular dose: 10 mg/kg bw route of administration: Intramuscular experiment type: SINGLE co-administered: |
AMDINOCILLIN serum | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
72.15 μg × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6311087/ |
15 mg/kg bw single, intramuscular dose: 15 mg/kg bw route of administration: Intramuscular experiment type: SINGLE co-administered: |
AMDINOCILLIN serum | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
58.81 μg × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6311087/ |
10 mg/kg bw single, intravenous dose: 10 mg/kg bw route of administration: Intravenous experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
T1/2
Value | Dose | Co-administered | Analyte | Population |
---|---|---|---|---|
0.886 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6311087/ |
15 mg/kg bw single, intravenous dose: 15 mg/kg bw route of administration: Intravenous experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
0.9 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/3377469/ |
400 mg single, oral dose: 400 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FED |
|
1 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/3377469/ |
400 mg single, oral dose: 400 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
1 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/3377469/ |
400 mg single, oral dose: 400 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
0.9 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/3377469/ |
400 mg single, oral dose: 400 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FED |
|
52.39 min EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6282208/ |
10 mg/kg bw 6 times / day steady-state, intravenous dose: 10 mg/kg bw route of administration: Intravenous experiment type: STEADY-STATE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
54.38 min EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6282208/ |
10 mg/kg bw single, intravenous dose: 10 mg/kg bw route of administration: Intravenous experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
0.96 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6311087/ |
10 mg/kg bw single, intramuscular dose: 10 mg/kg bw route of administration: Intramuscular experiment type: SINGLE co-administered: |
AMDINOCILLIN serum | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
0.859 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6311087/ |
15 mg/kg bw single, intramuscular dose: 15 mg/kg bw route of administration: Intramuscular experiment type: SINGLE co-administered: |
AMDINOCILLIN serum | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
0.888 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/6311087/ |
10 mg/kg bw single, intravenous dose: 10 mg/kg bw route of administration: Intravenous experiment type: SINGLE co-administered: |
AMDINOCILLIN plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
Doses
Dose | Population | Adverse events |
---|---|---|
500 mg single, intravenous Highest studied dose Dose: 500 mg Route: intravenous Route: single Dose: 500 mg Sources: Page: p.83 |
healthy, 25 - 43 n = 12 Health Status: healthy Age Group: 25 - 43 Population Size: 12 Sources: Page: p.83 |
|
10 mg/kg 4 times / day multiple, intravenous Studied dose Dose: 10 mg/kg, 4 times / day Route: intravenous Route: multiple Dose: 10 mg/kg, 4 times / day Sources: Page: p.110 |
unhealthy, 25-94 n = 38 Health Status: unhealthy Condition: gram-negative baciliary infections Age Group: 25-94 Sex: M+F Population Size: 38 Sources: Page: p.110 |
Other AEs: Diarrhea, Aspartate aminotransferase abnormal... Other AEs: Diarrhea (2.6%) Sources: Page: p.110Aspartate aminotransferase abnormal (10.52%) Alkaline phosphatase increased (7.9%) |
AEs
AE | Significance | Dose | Population |
---|---|---|---|
Aspartate aminotransferase abnormal | 10.52% | 10 mg/kg 4 times / day multiple, intravenous Studied dose Dose: 10 mg/kg, 4 times / day Route: intravenous Route: multiple Dose: 10 mg/kg, 4 times / day Sources: Page: p.110 |
unhealthy, 25-94 n = 38 Health Status: unhealthy Condition: gram-negative baciliary infections Age Group: 25-94 Sex: M+F Population Size: 38 Sources: Page: p.110 |
Diarrhea | 2.6% | 10 mg/kg 4 times / day multiple, intravenous Studied dose Dose: 10 mg/kg, 4 times / day Route: intravenous Route: multiple Dose: 10 mg/kg, 4 times / day Sources: Page: p.110 |
unhealthy, 25-94 n = 38 Health Status: unhealthy Condition: gram-negative baciliary infections Age Group: 25-94 Sex: M+F Population Size: 38 Sources: Page: p.110 |
Alkaline phosphatase increased | 7.9% | 10 mg/kg 4 times / day multiple, intravenous Studied dose Dose: 10 mg/kg, 4 times / day Route: intravenous Route: multiple Dose: 10 mg/kg, 4 times / day Sources: Page: p.110 |
unhealthy, 25-94 n = 38 Health Status: unhealthy Condition: gram-negative baciliary infections Age Group: 25-94 Sex: M+F Population Size: 38 Sources: Page: p.110 |
PubMed
Title | Date | PubMed |
---|---|---|
Penicillin-binding proteins and role of amdinocillin in causing bacterial cell death. | 1983 Aug 29 |
|
Efficacy of amdinocillin and lack of nephrotoxicity when combined with a second beta-lactam antibiotic for therapy of serious gram-negative bacillary infections. | 1983 Aug 29 |
|
Susceptibility of community Gram-negative urinary tract isolates to mecillinam and other oral agents. | 2001 Sep |
|
Shigella serotypes among hospitalized patients in urban Bangladesh and their antimicrobial resistance. | 2004 Aug |
|
Antimicrobial resistance in urinary bacterial isolates from pregnant women in rural Tanzania: implications for public health. | 2005 |
|
Prevalence of Shigella species and their antimicrobial resistance patterns in Eastern Nepal. | 2005 Dec |
|
Uncomplicated urinary tract infections. Bacterial findings and efficacy of empirical antibacterial treatment. | 2005 Jun |
|
Susceptibility testing of urinary isolates of Escherichia coli to mecillinam using NCCLS methodology. | 2005 Mar |
|
Intracellular persistence of Escherichia coli in urinary bladders from mecillinam-treated mice. | 2005 Mar |
|
Iron limitation induces SpoT-dependent accumulation of ppGpp in Escherichia coli. | 2005 May |
|
Isolation and characterization of provisional serovar Shigella boydii E16553 from diarrhoeal patients in Bangladesh. | 2005 May |
|
Partition of old murein in small patches over the entire wall of E. coli cells forced to grow as a coccoid. | 2006 Apr |
|
[Increasing antibiotic resistance in urinary tract infections]. | 2006 Apr 6 |
|
The emerging strains of Shigella dysenteriae type 2 in Bangladesh are clonal. | 2006 Dec |
|
Activity of mecillinam against ESBL producers in vitro. | 2006 Feb |
|
Activity of mecillinam against AmpC beta-lactamase-producing Escherichia coli. | 2006 Jul |
|
High-level resistance to mecillinam produced by inactivation of soluble lytic transglycosylase in Salmonella enterica serovar Typhimurium. | 2006 Mar |
|
Antimicrobial resistance among enterobacteriaceae causing uncomplicated urinary tract infections in Mauritius: consequences of past misuse of antibiotics. | 2007 Apr |
|
The essential peptidoglycan glycosyltransferase MurG forms a complex with proteins involved in lateral envelope growth as well as with proteins involved in cell division in Escherichia coli. | 2007 Aug |
|
Spontaneous zygogenesis (Z-mating) in mecillinam-rounded bacteria. | 2007 Dec |
|
The diversity of multi-drug resistance profiles in tetracycline-resistant Vibrio species isolated from coastal sediments and seawater. | 2007 Feb |
|
DNA and origin region segregation are not affected by the transition from rod to sphere after inhibition of Escherichia coli MreB by A22. | 2007 Jul |
|
Increasing spectrum in antimicrobial resistance of Shigella isolates in Bangladesh: resistance to azithromycin and ceftriaxone and decreased susceptibility to ciprofloxacin. | 2007 Jun |
|
Function of penicillin-binding protein 2 in viability and morphology of Pseudomonas aeruginosa. | 2007 Mar |
|
A novel serovar of Shigella dysenteriae from patients with diarrhoea in Bangladesh. | 2007 May |
|
Characterization of HMW-PBPs from the rod-shaped actinomycete Corynebacterium glutamicum: peptidoglycan synthesis in cells lacking actin-like cytoskeletal structures. | 2007 Nov |
|
Evolutionary diversification of plant shikimate kinase gene duplicates. | 2008 Dec |
|
In vitro interaction between mecillinam and piperacillin-tazobactam in the presence of azithromycin against members of the Enterobacteriaceae family and Pseudomonas aeruginosa. | 2008 Jan |
|
Dissemination of multidrug-resistant bacteria into the Arctic. | 2008 Jan |
|
Transfer of antimicrobial resistance plasmids from Klebsiella pneumoniae to Escherichia coli in the mouse intestine. | 2008 Nov |
|
Surveillance study in Europe and Brazil on clinical aspects and Antimicrobial Resistance Epidemiology in Females with Cystitis (ARESC): implications for empiric therapy. | 2008 Nov |
|
Endemic and epidemic lineages of Escherichia coli that cause urinary tract infections. | 2008 Oct |
|
Mecillinam: a low-risk antimicrobial agent for induction of Clostridium difficile infection in an in vitro human gut model. | 2009 Apr |
|
Secondary syphilis with exclusive peno-scrotal localization. | 2009 Dec |
|
RodZ, a new player in bacterial cell morphogenesis. | 2009 Feb 4 |
|
Actinomyces species: A danish survey on human infections and microbiological characteristics. | 2009 Jul 23 |
|
Multi-resistant Escherichia coli and mycotic aneurysm: two case reports. | 2009 Mar 10 |
|
Bend into shape. | 2009 May 6 |
|
Influence of RpoS, cAMP-receptor protein, and ppGpp on expression of the opgGH operon and osmoregulated periplasmic glucan content of Salmonella enterica serovar Typhimurium. | 2009 Nov |
|
The ARESC study: an international survey on the antimicrobial resistance of pathogens involved in uncomplicated urinary tract infections. | 2009 Nov |
|
Empiric antibiotic therapy in acute uncomplicated urinary tract infections and fluoroquinolone resistance: a prospective observational study. | 2009 Oct 24 |
|
Low frequency of antibiotic resistance among urine isolates of Escherichia coli in the community, despite a major hospital outbreak with Klebsiella pneumoniae producing CTX-M-15 in Uppsala County. | 2010 Apr |
|
[Clinical aspects and epidemiology of uncomplicated cystitis in women. German results of the ARESC Study]. | 2010 Feb |
|
Molecular characterisation of trimethoprim resistance in Escherichia coli and Klebsiella pneumoniae during a two year intervention on trimethoprim use. | 2010 Feb 16 |
|
Activity of mecillinam against Escherichia coli resistant to third-generation cephalosporins. | 2010 Jan |
|
Acute uncomplicated cystitis: from surveillance data to a rationale for empirical treatment. | 2010 Jan |
|
Septal and lateral wall localization of PBP5, the major D,D-carboxypeptidase of Escherichia coli, requires substrate recognition and membrane attachment. | 2010 Jul |
|
Do different susceptibility breakpoints affect the selection of antimicrobials for treatment of uncomplicated cystitis? | 2010 Oct |
|
Extended-spectrum β-lactamases in Gram Negative Bacteria. | 2010 Sep |
|
Molecular and evolutionary bases of within-patient genotypic and phenotypic diversity in Escherichia coli extraintestinal infections. | 2010 Sep 30 |
Patents
Sample Use Guides
Parenteral
Urinary tract infections
Adult: 800 mg every 6-8 hr by IM, slow IV inj or IV infusion. Severe infections: Up to 60 mg/kg/day.
Route of Administration:
Parenteral
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/11120983
Amdinocillin (Mecillinam) selectively inhibited PBP1, with a 50% inhibitory concentration for PBP1 binding (0.2 ug/ml) similar to the MIC (0.1 ug/ml) and minimum bactericidal concentration (0.25 ug/ml).
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:26:08 UTC 2023
by
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on
Fri Dec 15 15:26:08 UTC 2023
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Record UNII |
48FX7N21H2
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Record Status |
Validated (UNII)
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Record Version |
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SUB03884MIG
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102745
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51213
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32887-03-9
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CHEMBL1650818
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m1654
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DBSALT001943
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48FX7N21H2
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251-278-7
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DTXSID1045453
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100000091362
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115162
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