N-(4-(1-CYCLOPROPYL-4-FLUORO-2-METHYL-1H-BENZO(D)IMIDAZOL-6-YL)-5-FLUOROPYRIMIDIN-2-YL)-6-(2-(DIMETHYLAMINO)ETHYL)-5,6,7,8-TETRAHYDRO-L,6-NAPHTHYRIDIN-2-AMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C27H30F2N8
Molecular Weight	504.5775
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of N-(4-(1-CYCLOPROPYL-4-FLUORO-2-METHYL-1H-BENZO(D)IMIDAZOL-6-YL)-5-FLUOROPYRIMIDIN-2-YL)-6-(2-(DIMETHYLAMINO)ETHYL)-5,6,7,8-TETRAHYDRO-L,6-NAPHTHYRIDIN-2-AMINE

Structure Search

SMILES

CN(C)CCN1CCC2=C(C1)C=CC(NC3=NC=C(F)C(=N3)C4=CC(F)=C5N=C(C)N(C6CC6)C5=C4)=N2

InChI

InChIKey=UZUCFTPPULEGQO-UHFFFAOYSA-N

InChI=1S/C27H30F2N8/c1-16-31-26-20(28)12-18(13-23(26)37(16)19-5-6-19)25-21(29)14-30-27(34-25)33-24-7-4-17-15-36(11-10-35(2)3)9-8-22(17)32-24/h4,7,12-14,19H,5-6,8-11,15H2,1-3H3,(H,30,32,33,34)

HIDE SMILES / InChI

Molecular Formula	C27H30F2N8
Molecular Weight	504.5775
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:29:54 UTC 2023` Edited by `admin` on `Sat Dec 16 18:29:54 UTC 2023`
Record UNII	484EDA7KEM
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

N-(4-(1-CYCLOPROPYL-4-FLUORO-2-METHYL-1H-BENZO(D)IMIDAZOL-6-YL)-5-FLUOROPYRIMIDIN-2-YL)-6-(2-(DIMETHYLAMINO)ETHYL)-5,6,7,8-TETRAHYDRO-L,6-NAPHTHYRIDIN-2-AMINE

Systematic Name

English

1,6-NAPHTHYRIDINE-6(5H)-ETHANAMINE, 2-((4-(1-CYCLOPROPYL-4-FLUORO-2-METHYL-1H-BENZIMIDAZOL-6-YL)-5-FLUORO-2-PYRIMIDINYL)AMINO)-7,8-DIHYDRO-N,N-DIMETHYL-

Common Name

English

Code System Code Type Description

FDA UNII

484EDA7KEM

Created by admin on Sat Dec 16 18:29:54 UTC 2023 , Edited by admin on Sat Dec 16 18:29:54 UTC 2023

PRIMARY

PUBCHEM

130196740

Created by admin on Sat Dec 16 18:29:54 UTC 2023 , Edited by admin on Sat Dec 16 18:29:54 UTC 2023

PRIMARY

CAS

2102887-41-0

Created by admin on Sat Dec 16 18:29:54 UTC 2023 , Edited by admin on Sat Dec 16 18:29:54 UTC 2023

PRIMARY

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CYCLIN-DEPENDENT KINASE 6

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Related Record Type Details


					484EDA7KEM

N-(4-(1-CYCLOPROPYL-4-FLUORO-2-METHYL-1H-BENZO(D)IMIDAZOL-6-YL)-5-FLUOROPYRIMIDIN-2-YL)-6-(2-(DIMETHYLAMINO)ETHYL)-5,6,7,8-TETRAHYDRO-L,6-NAPHTHYRIDIN-2-AMINE

ACTIVE MOIETY

Amount:

Name	Property Type	Parameters
BRAIN/PLASMA RATIO	PHARMACOKINETIC	Species BIOLOGICAL Dose PHARMACOKINETIC Time after administration PHARMACOKINETIC

BRAIN/PLASMA RATIO	PHARMACOKINETIC	Time after administration PHARMACOKINETIC Species BIOLOGICAL Dose PHARMACOKINETIC

BRAIN/PLASMA RATIO	PHARMACOKINETIC	Dose PHARMACOKINETIC Time after administration PHARMACOKINETIC Species BIOLOGICAL