Mitoquinone is a mitochondria-targeted antioxidant designed to accumulate within mitochondria in vivo in order to protect against oxidative damage. Mitoquinone comprises a positively charged lipophilic cation that drives its extensive accumulation within the negatively charged mitochondria inside cells. Because of the large mitochondria membrane potential, the cations accumulate within cellular mitochondria up to 1,000 fold, compared to non-targeted antioxidants such as Coenzyme Q or its analogs, enabling the antioxidant moiety to block lipid peroxidation and protect mitochondria from oxidative damage. By selectively blocking mitochondrial oxidative damage, it prevents cell death. Mitoquinone may help to prevent the nerve cell damage that leads to Parkinson's disease.