Formamide

Details

Stereochemistry	ACHIRAL
Molecular Formula	CH3NO
Molecular Weight	45.0406
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC=O

InChI

InChIKey=ZHNUHDYFZUAESO-UHFFFAOYSA-N

InChI=1S/CH3NO/c2-1-3/h1H,(H2,2,3)

HIDE SMILES / InChI

Molecular Formula	CH3NO
Molecular Weight	45.0406
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Sequence-dependent effects of ZD1839 ('Iressa') in combination with cytotoxic treatment in human head and neck cancer.	2002-03-04	11875748
Inhibitory effect on expression of angiogenic factors by antiangiogenic agents in renal cell carcinoma.	2002-03-04	11875741
Leishmanicidal activity of some aliphatic diamines and amino-alcohols.	2002-02-25	11844694
Reaction mechanism of GTP cyclohydrolase I: single turnover experiments using a kinetically competent reaction intermediate.	2002-02-22	11866535
Characterization of the carboxylate delivery module of transcarboxylase: following spontaneous decarboxylation of the 1.3S-CO2- subunit by NMR and FTIR spectroscopies.	2002-02-19	11841210
Enantioselective carbon-hydrogen insertion is an effective and efficient methodology for the synthesis of (R)-(-)-baclofen.	2002-02-09	11835561
Mxi1 inhibits the proliferation of U87 glioma cells through down-regulation of cyclin B1 gene expression.	2002-02-01	11875718
Telomere length measurement by fluorescence in situ hybridization and flow cytometry: tips and pitfalls.	2002-02-01	11813198
Comparison of three different anionic surfactants for the separation of hydrophobic compounds by nonaqueous capillary electrophoresis.	2002-02	11870742
Synthesis of unsymmetrical aroyl acyl imides by aminocarbonylation of aryl bromides.	2002-01-25	11798337
Rate acceleration of the Baylis-Hillman reaction in polar solvents (water and formamide). Dominant role of hydrogen bonding, not hydrophobic effects, is implicated.	2002-01-25	11798324
Identification of molecular markers for the early detection of human squamous cell carcinoma of the uterine cervix.	2002-01-21	11870519
N-acyl-L-phenylalanine derivatives as potent VLA-4 antagonists that mimic a cyclic peptide conformation.	2002-01-21	11755339
Synthesis, stability, and conformation of the formamidopyrimidine G DNA lesion.	2002-01-04	11822460
Solute-solvent interactions in micellar electrokinetic chromatography: IV. Characterization of electroosmotic flow and micellar markers.	2002-01	11824622
Chiral separation by electrokinetic capillary chromatography using newly synthesized linear polymers containing L-amino acid moieties.	2002-01	11817735
Determination of key metabolites during biodegradation of hexahydro-1,3,5-trinitro-1,3,5-triazine with Rhodococcus sp. strain DN22.	2002-01	11772623
Peptidomimetic glutathione analogues as novel gammaGT stable GST inhibitors.	2002-01	11738622
Evaluation of differential gene expression during behavioral development in the honeybee using microarrays and northern blots.	2002	11864369
Cloning and characterization of the rat homologues of the Inhibitor of Apoptosis protein 1, 2, and 3 genes.	2002	11860601
Phorbol esters and cAMP differentially regulate the expression of CD4 and CD8 in human thymocytes.	2002	11835689
Experimental validation of Gaussian-3 lithium cation affinities of amides: implications for the gas-phase lithium cation basicity scale.	2002	11803545
Stabilities of ion/radical adducts in the liquid phase as derived from the dependence of electrochemical cleavage reactivities upon solvent.	2001-12-05	11724597
Hydantoinases and related enzymes as biocatalysts for the synthesis of unnatural chiral amino acids.	2001-12	11849938
A probe design for the acquisition of homonuclear, heteronuclear, and inverse detected NMR spectra from multiple samples.	2001-12	11740902
Therapeutic potential of a novel synthetic selectin blocker, OJ-R9188, in allergic dermatitis.	2001-12	11724756
Progress in Karl Fischer coulometry using diaphragm-free cells.	2001-11-15	11816595
Hydroxyurea induces site-specific DNA damage via formation of hydrogen peroxide and nitric oxide.	2001-11	11714440
Motility of single one-headed kinesin molecules along microtubules.	2001-11	11606295
Synthesis, characterization and reactions of 2-deoxo-5-deazaalloxazines.	2001-11	11597481
Conversion of azomethine moiety to carboxamido group at cobalt(III) center in model complexes of Co-containing nitrile hydratase.	2001-10-08	11578187
Rapid method for comparing the cytotoxicity of organic solvents and their ability to destabilize proteins of the erythrocyte membrane.	2001-10	11683129
Mutation analysis of TP53 exons 5-8 by automated constant denaturant capillary electrophoresis.	2001-09-13	11553863
Polysulfonylamines. CXLV. N-diethylcarbamoyl-o-benzenedisulfonimide, a urea with non-planar geometry at nitrogen and an amide single bond.	2001-09	11588387
Fluorescent coumarin-labeled nucleotides to measure ADP release from actomyosin.	2001-09	11509369
The enhancement of PCR amplification by low molecular-weight sulfones.	2001-08-22	11675022
Identification of connexin43 (alpha1) gap junction gene mutations in patients with hypoplastic left heart syndrome by denaturing gradient gel electrophoresis (DGGE).	2001-08-08	11470490
Design, synthesis, and structure-activity relationships of macrocyclic hydroxamic acids that inhibit tumor necrosis factor alpha release in vitro and in vivo.	2001-08-02	11472217
Comparison of the antiviral activity of hydrophobic amino acid phosphoramidate monoesters of 2'3'-dideoxyadenosine (DDA) and 3'-azido-3'-deoxythymidine (AZT).	2001-08	11554546
Urea substitutes toxic formamide as destabilizing agent in nucleic acid hybridizations with RNA probes.	2001-08	11545392
Interactions between organic flocculant PAN-DCD and dyes.	2001-08	11513420
Detection of DNA adducts of benzo[a]pyrene using immunoelectrophoresis with laser-induced fluorescence. Analysis of A549 cells.	2001-07-27	11521887
Alterations of E-cadherin and beta-catenin in gastric cancer.	2001	11747475
Analysis of amino acids as formamidene butyl esters by electrospray ionization tandem mass spectrometry.	2001	11746885
Potential of (GATA)n microsatellites from rice for inter- and intra-specific variability studies.	2001	11710957
Poly purine.pyrimidine sequences upstream of the beta-galactosidase gene affect gene expression in Saccharomyces cerevisiae.	2001	11696239
Characterization of alternatively spliced products and tissue-specific isoforms of USP28 and USP25.	2001	11597335
A rapid method to map mutations in Drosophila.	2001	11574055
Rearrangement with formamide extrusion in the electrospray mass spectra of aminoacylbenzylamines.	2001	11507763
Identification of the gene encoding Brain Cell Membrane Protein 1 (BCMP1), a putative four-transmembrane protein distantly related to the Peripheral Myelin Protein 22 / Epithelial Membrane Proteins and the Claudins.	2001	11472633

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:34:00 GMT 2025` Edited by `admin` on `Mon Mar 31 18:34:00 GMT 2025`
Record UNII	4781T907ZS
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Formamide

Systematic Name

English

NSC-748

Preferred Name

English

Formamide [USP-RS]

Common Name

English

Formamide [HSDB]

Common Name

English

Methanamide

Systematic Name

English

Formimidic acid

Systematic Name

English

Carbamaldehyde

Common Name

English

Formamide [MI]

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID8025337