Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H20N4O4 |
| Molecular Weight | 380.3972 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=C2OCC3(CC3)C2=C(OC4=NC=C(C=N4)N5C(=O)NC(C)(C)C5=O)C=C1
InChI
InChIKey=JYHHQTRVJFMEGR-UHFFFAOYSA-N
InChI=1S/C20H20N4O4/c1-11-4-5-13(14-15(11)27-10-20(14)6-7-20)28-17-21-8-12(9-22-17)24-16(25)19(2,3)23-18(24)26/h4-5,8-9H,6-7,10H2,1-3H3,(H,23,26)
| Molecular Formula | C20H20N4O4 |
| Molecular Weight | 380.3972 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Tue Apr 01 20:53:23 GMT 2025
by
admin
on
Tue Apr 01 20:53:23 GMT 2025
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| Record UNII |
46P8AHZ243
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| Record Status |
Validated (UNII)
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| Record Version |
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Preferred Name | English | ||
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Code | English | ||
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Systematic Name | English | ||
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Systematic Name | English |
| Classification Tree | Code System | Code | ||
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FDA ORPHAN DRUG |
579217
Created by
admin on Tue Apr 01 20:53:23 GMT 2025 , Edited by admin on Tue Apr 01 20:53:23 GMT 2025
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1380696-64-9
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57411069
Created by
admin on Tue Apr 01 20:53:23 GMT 2025 , Edited by admin on Tue Apr 01 20:53:23 GMT 2025
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46P8AHZ243
Created by
admin on Tue Apr 01 20:53:23 GMT 2025 , Edited by admin on Tue Apr 01 20:53:23 GMT 2025
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300000047456
Created by
admin on Tue Apr 01 20:53:23 GMT 2025 , Edited by admin on Tue Apr 01 20:53:23 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET->POSITIVE ALLOSTERIC MODULATOR (PAM) |
AUT00206 positively modulates recombinant human Kv3.1 and Kv3.2 mediated currents, associated with a leftward shift of channel activation.
The compound has a weaker effect on Kv3.3 and Kv3.4 channels, and little or no effect on other ion channels tested.
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TARGET->POSITIVE ALLOSTERIC MODULATOR (PAM) |
AUT00206 positively modulates recombinant human Kv3.1 and Kv3.2 mediated currents, associated with a leftward shift of channel activation.
The compound has a weaker effect on Kv3.3 and Kv3.4 channels, and little or no effect on other ion channels tested.
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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