U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 21:28:27 GMT 2025
Edited
by admin
on Mon Mar 31 21:28:27 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
45M75JVK38
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BOCOCIZUMAB
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
bococizumab [INN]
Preferred Name English
Bococizumab [WHO-DD]
Common Name English
PF-04950615
Code English
IMMUNOGLOBULIN G2, ANTI-(HUMAN NEURAL APOPTOSIS-REGULATED PROTEINASE 1) (HUMAN-MUS MUSCULUS MONOCLONAL PF-04950615 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL PF-04950615 LIGHT CHAIN, DIMER
Common Name English
BOCOCIZUMAB [USAN]
Common Name English
RN-316
Code English
IMMUNOGLOBULIN G2, ANTI-(HUMAN NEURAL APOPTOSIS-REGULATED PROTEINASE 1)(HUMAN-MUS MUSCULUS MONOCLONAL PF-04950615 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL PF-04950615 LIGHT CHAIN, DIMER
Common Name English
BOCOCIZUMAB [JAN]
Common Name English
RN316
Code English
Code System Code Type Description
DRUG BANK
DB12456
Created by admin on Mon Mar 31 21:28:27 GMT 2025 , Edited by admin on Mon Mar 31 21:28:27 GMT 2025
PRIMARY
NCI_THESAURUS
C166723
Created by admin on Mon Mar 31 21:28:27 GMT 2025 , Edited by admin on Mon Mar 31 21:28:27 GMT 2025
PRIMARY
FDA UNII
45M75JVK38
Created by admin on Mon Mar 31 21:28:27 GMT 2025 , Edited by admin on Mon Mar 31 21:28:27 GMT 2025
PRIMARY
USAN
AB-55
Created by admin on Mon Mar 31 21:28:27 GMT 2025 , Edited by admin on Mon Mar 31 21:28:27 GMT 2025
PRIMARY
SMS_ID
100000165896
Created by admin on Mon Mar 31 21:28:27 GMT 2025 , Edited by admin on Mon Mar 31 21:28:27 GMT 2025
PRIMARY
INN
9840
Created by admin on Mon Mar 31 21:28:27 GMT 2025 , Edited by admin on Mon Mar 31 21:28:27 GMT 2025
PRIMARY
ChEMBL
CHEMBL3137349
Created by admin on Mon Mar 31 21:28:27 GMT 2025 , Edited by admin on Mon Mar 31 21:28:27 GMT 2025
PRIMARY
WIKIPEDIA
Bococizumab
Created by admin on Mon Mar 31 21:28:27 GMT 2025 , Edited by admin on Mon Mar 31 21:28:27 GMT 2025
PRIMARY
CAS
1407495-02-6
Created by admin on Mon Mar 31 21:28:27 GMT 2025 , Edited by admin on Mon Mar 31 21:28:27 GMT 2025
PRIMARY
EVMPD
SUB179790
Created by admin on Mon Mar 31 21:28:27 GMT 2025 , Edited by admin on Mon Mar 31 21:28:27 GMT 2025
PRIMARY
From To
1_22 1_96
1_132 3_214
1_145 1_201
1_220 2_220
1_221 2_221
1_224 2_224
1_227 2_227
1_258 1_318
1_364 1_422
2_22 2_96
2_132 4_214
2_145 2_201
2_258 2_318
2_364 2_422
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Link Type Site
N 1_294
N 2_294
Related Record Type Details
PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9
TARGET -> INHIBITOR
Related Record Type Details
BOCOCIZUMAB
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
amino acid substitution [1_1] [2_1] PIDOLIC ACID SZB83O1W42
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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