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Details

Stereochemistry ACHIRAL
Molecular Formula C4H10O2S2
Molecular Weight 154.251
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-HYDROXYETHYL DISULFIDE

SMILES

OCCSSCCO

InChI

InChIKey=KYNFOMQIXZUKRK-UHFFFAOYSA-N
InChI=1S/C4H10O2S2/c5-1-3-7-8-4-2-6/h5-6H,1-4H2

HIDE SMILES / InChI

Molecular Formula C4H10O2S2
Molecular Weight 154.251
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
A bioactive probe of the oxidative pentose phosphate cycle: novel strategy to reverse radioresistance in glucose deprived human colon cancer cells.
2013-02
Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE.
2010-09-22
Amyloid-like aggregates of the yeast prion protein ure2 enter vertebrate cells by specific endocytotic pathways and induce apoptosis.
2010-09-02
Expression and characterization of three new glutathione transferases, an epsilon (AcGSTE2-2), omega (AcGSTO1-1), and theta (AcGSTT1-1) from Anopheles cracens (Diptera: Culicidae), a major Thai malaria vector.
2010-03
pO(2)-dependent NO production determines OPPC activity in macrophages.
2010-01-15
Glutathione-mediated biodegradable polyurethanes derived from L-arabinitol.
2010-01-11
Mitochondrial Thioredoxin-Glutathione Reductase from Larval Taenia crassiceps (Cysticerci).
2010
Proximity-based protein thiol oxidation by H2O2-scavenging peroxidases.
2009-11-13
Cloning, expression, and characterization of an enzyme possessing both glutaredoxin and dehydroascorbate reductase activity from Taiwanofungus camphorata.
2009-11-11
2-DE analysis indicates that Acinetobacter baumannii displays a robust and versatile metabolism.
2009-09-28
An update on the mouse liver proteome.
2009-09-08
Improved resolution in the acidic and basic region of 2-DE of insect antennae proteins using hydroxyethyl disulfide.
2009-08
Analysis of the structure and function of YfcG from Escherichia coli reveals an efficient and unique disulfide bond reductase.
2009-07-21
Human G-CSF synthesis using stress-responsive bacterial proteins.
2009-07
Receptor-associated protein (RAP) has two high-affinity binding sites for the low-density lipoprotein receptor-related protein (LRP): consequences for the chaperone functions of RAP.
2009-06-26
New insights into the biodegradation of thiodiglycol, the hydrolysis product of Yperite (sulfur mustard gas).
2009-04
Trypanosoma cruzi alkaline 2-DE: Optimization and application to comparative proteome analysis of flagellate life stages.
2008-09-08
Water-induced hydrophobicity of soy protein materials containing 2,2-diphenyl-2-hydroxyethanoic acid.
2008-09
Plant protein isolation and stabilization for enhanced resolution of two-dimensional polyacrylamide gel electrophoresis.
2008-08-15
Selenoglutaredoxin as a glutathione peroxidase mimic.
2008-07-02
Multiple stressor-induced proteome responses of Escherichia coli BL21(DE3).
2008-05
Two novel monothiol glutaredoxins from Saccharomyces cerevisiae provide further insight into iron-sulfur cluster binding, oligomerization, and enzymatic activity of glutaredoxins.
2008-02-05
Cloning, functional analysis, and mitochondrial localization of Trypanosoma brucei monothiol glutaredoxin-1.
2008-01
Uptake and reduction of alpha-lipoic acid by human erythrocytes.
2007-10
Combined cup loading, bis(2-hydroxyethyl) disulfide, and protein precipitation protocols to improve the alkaline proteome of Lactobacillus hilgardii.
2007-05
The two-domain structure of 5'-adenylylsulfate (APS) reductase from Enteromorpha intestinalis is a requirement for efficient APS reductase activity.
2007-01-16
Proteomic analysis of human plasma proteins by two-dimensional gel electrophoresis and by antibody arrays following depletion of high-abundance proteins.
2007
Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.
2006-03-08
Mechanistic insight provided by glutaredoxin within a fusion to redox-sensitive yellow fluorescent protein.
2006-02-21
A simplified 2-D electrophoresis protocol with the aid of an organic disulfide.
2005-08
A novel monothiol glutaredoxin (Grx4) from Escherichia coli can serve as a substrate for thioredoxin reductase.
2005-07-01
Expression and oxidative stress tolerance studies of glutaredoxin from cyanobacterium Synechocystis sp. PCC 6803 in Escherichia coli.
2005-07
Optimised two-dimensional electrophoresis procedures for the protein characterisation of structural tissues.
2005-05
Fishing of beta-amylase with a SAM of alpha-cyclodextrin-poly- (ethylene glycol) conjugate.
2004-11-15
Analyzing alkaline proteins in human colon crypt proteome.
2004-09-14
Improved resolution of the human adipose tissue proteome at alkaline and wide range pH by the addition of hydroxyethyl disulfide.
2004-02
Facile synthesis of chlorophyll analog possessing a disulfide bond and formation of self-assembled monolayer on gold surface.
2004-01-23
Purification, characterization and kinetic properties of the multifunctional thioredoxin-glutathione reductase from Taenia crassiceps metacestode (cysticerci).
2004-01
Plasmoredoxin, a novel redox-active protein unique for malarial parasites.
2003-03
Characterization of the human Omega class glutathione transferase genes and associated polymorphisms.
2003-03
Organic disulfides as a means to generate streak-free two-dimensional maps with narrow range basic immobilized pH gradient strips as first dimension.
2002-11
Two isoforms of Saccharomyces cerevisiae glutaredoxin 2 are expressed in vivo and localize to different subcellular compartments.
2002-06-15
GSTB1-1 from Proteus mirabilis: a snapshot of an enzyme in the evolutionary pathway from a redox enzyme to a conjugating enzyme.
2002-05-24
Mutation in the glucose-6-phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress.
2002-03-22
Exploring the active site of plant glutaredoxin by site-directed mutagenesis.
2002-01-30
Plasmodium falciparum possesses a classical glutaredoxin and a second, glutaredoxin-like protein with a PICOT homology domain.
2001-10-05
Human lens thioltransferase: cloning, purification, and function.
2001-03
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:29:50 GMT 2025
Edited
by admin
on Mon Mar 31 19:29:50 GMT 2025
Record UNII
45543L74BS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-33920
Preferred Name English
2-HYDROXYETHYL DISULFIDE
Systematic Name English
2-MERCAPTOETHANOL DISULFIDE
Systematic Name English
2,2'-DITHIOBISETHANOL
Systematic Name English
ETHANOL, 2,2'-DITHIOBIS-
Systematic Name English
2-HYDROXYETHANE DISULFIDE
Common Name English
.BETA.-HYDROXYETHYL DISULFIDE
Systematic Name English
HYDROXYETHYL DISULPHIDE, 2-
Systematic Name English
ETHANOL, 2,2'-DITHIODI-
Systematic Name English
3,4-DITHIA-1,6-HEXANEDIOL
Systematic Name English
2,2'-DITHIODIETHANOL
Systematic Name English
Code System Code Type Description
DRUG BANK
DB02486
Created by admin on Mon Mar 31 19:29:50 GMT 2025 , Edited by admin on Mon Mar 31 19:29:50 GMT 2025
PRIMARY
ECHA (EC/EINECS)
217-576-6
Created by admin on Mon Mar 31 19:29:50 GMT 2025 , Edited by admin on Mon Mar 31 19:29:50 GMT 2025
PRIMARY
CAS
1892-29-1
Created by admin on Mon Mar 31 19:29:50 GMT 2025 , Edited by admin on Mon Mar 31 19:29:50 GMT 2025
PRIMARY
EPA CompTox
DTXSID4044404
Created by admin on Mon Mar 31 19:29:50 GMT 2025 , Edited by admin on Mon Mar 31 19:29:50 GMT 2025
PRIMARY
NSC
33920
Created by admin on Mon Mar 31 19:29:50 GMT 2025 , Edited by admin on Mon Mar 31 19:29:50 GMT 2025
PRIMARY
FDA UNII
45543L74BS
Created by admin on Mon Mar 31 19:29:50 GMT 2025 , Edited by admin on Mon Mar 31 19:29:50 GMT 2025
PRIMARY
CHEBI
43136
Created by admin on Mon Mar 31 19:29:50 GMT 2025 , Edited by admin on Mon Mar 31 19:29:50 GMT 2025
PRIMARY
PUBCHEM
15906
Created by admin on Mon Mar 31 19:29:50 GMT 2025 , Edited by admin on Mon Mar 31 19:29:50 GMT 2025
PRIMARY