Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C26H43NO5 |
Molecular Weight | 449.6233 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 10 / 10 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)NCC(O)=O
InChI
InChIKey=GHCZAUBVMUEKKP-GYPHWSFCSA-N
InChI=1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-/m1/s1
Molecular Formula | C26H43NO5 |
Molecular Weight | 449.6233 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 9 / 10 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Spontaneous nitric oxide in hepatocyte monolayers and inhibition of compound-induced apoptosis. | 2001 Dec |
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Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation. | 2003 Aug |
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Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes. | 2003 Dec |
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Gallium-67 activated charcoal: a new method for preparation of radioactive capsules for colonic transit study. | 2003 Jun |
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Bile salt-induced hepatocyte apoptosis involves epidermal growth factor receptor-dependent CD95 tyrosine phosphorylation. | 2003 Sep |
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Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump. | 2005 Jan |
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Bile salts inhibit growth and induce apoptosis of culture human normal esophageal mucosal epithelial cells. | 2005 Nov 7 |
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Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione. | 2006 Apr |
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Sulfasalazine reduces bile acid induced apoptosis in human hepatoma cells and perfused rat livers. | 2006 May |
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Hydrophobic bile salts induce hepatocyte shrinkage via NADPH oxidase activation. | 2007 |
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Taurodeoxycholate modulates apical Cl-/OH- exchange activity in Caco2 cells. | 2007 May |
|
Mitochondrial-driven ubiquinone enhances extracellular calcium-dependent nitric oxide production and reduces glycochenodeoxycholic acid-induced cell death in hepatocytes. | 2009 Dec |
|
Interpreting metabolomic profiles using unbiased pathway models. | 2010 Feb 26 |
|
Calcium-dependent nitric oxide production is involved in the cytoprotective properties of n-acetylcysteine in glycochenodeoxycholic acid-induced cell death in hepatocytes. | 2010 Jan 15 |
|
Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis. | 2012 |
|
Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. | 2012 May |
Substance Class |
Chemical
Created
by
admin
on
Edited
Thu Jul 06 07:24:19 UTC 2023
by
admin
on
Thu Jul 06 07:24:19 UTC 2023
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Record UNII |
451ZNJ667Y
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Record Status |
Validated (UNII)
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Record Version |
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-
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LOINC |
2066-9
Created by
admin on Thu Jul 06 07:24:19 UTC 2023 , Edited by admin on Thu Jul 06 07:24:19 UTC 2023
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Code System | Code | Type | Description | ||
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Glycochenodeoxycholic acid
Created by
admin on Thu Jul 06 07:24:19 UTC 2023 , Edited by admin on Thu Jul 06 07:24:19 UTC 2023
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DTXSID301020165
Created by
admin on Thu Jul 06 07:24:19 UTC 2023 , Edited by admin on Thu Jul 06 07:24:19 UTC 2023
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36274
Created by
admin on Thu Jul 06 07:24:19 UTC 2023 , Edited by admin on Thu Jul 06 07:24:19 UTC 2023
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12544
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admin on Thu Jul 06 07:24:19 UTC 2023 , Edited by admin on Thu Jul 06 07:24:19 UTC 2023
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DB02123
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admin on Thu Jul 06 07:24:19 UTC 2023 , Edited by admin on Thu Jul 06 07:24:19 UTC 2023
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640-79-9
Created by
admin on Thu Jul 06 07:24:19 UTC 2023 , Edited by admin on Thu Jul 06 07:24:19 UTC 2023
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451ZNJ667Y
Created by
admin on Thu Jul 06 07:24:19 UTC 2023 , Edited by admin on Thu Jul 06 07:24:19 UTC 2023
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PRIMARY |
Related Record | Type | Details | ||
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TRANSPORTER -> SUBSTRATE |