GLYCOCHENODEOXYCHOLIC ACID

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C26H43NO5
Molecular Weight	449.6233
Optical Activity	UNSPECIFIED
Defined Stereocenters	10 / 10
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)NCC(O)=O

InChI

InChIKey=GHCZAUBVMUEKKP-GYPHWSFCSA-N

InChI=1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C26H43NO5
Molecular Weight	449.6233
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	9 / 10
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Solubilization of drugs by physiological mixtures of bile salts.	2002 Aug	12240947
[Release of cytochrome C with the interaction of bilirubin, amyloid beta-peptide and glycochenodeoxycholate from isolated mitochondria].	2002 Jul-Aug	12525020
Membrane structural changes support the involvement of mitochondria in the bile salt-induced apoptosis of rat hepatocytes.	2002 Nov	12401120
Bile salts inhibit growth and induce apoptosis of culture human normal esophageal mucosal epithelial cells.	2005 Nov 7	16425417
Hydrophobic bile salts induce hepatocyte shrinkage via NADPH oxidase activation.	2007	17310103
Determination of intralumenal individual bile acids by HPLC with charged aerosol detection.	2008 Dec	18693215

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:03:04 GMT 2023` Edited by `admin` on `Sat Dec 16 01:03:04 GMT 2023`
Record UNII	451ZNJ667Y
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GLYCOCHENODEOXYCHOLIC ACID

Common Name

English

12-DEOXYCHOLYLGLYCINE

Common Name

English

CHENODEOXYGLYCOCHOLIC ACID

Common Name

English

12-DESOXYCHOLYLGLYCINE

Common Name

English

GLYCYLCHENODEOXYCHOLIC ACID

Common Name

English

GLYCINE, N-(3.ALPHA.,7.ALPHA.-DIHYDROXY-5.BETA.-CHOLAN-24-OYL)-

Systematic Name

English

GLYCINE, N-((3.ALPHA.,5.BETA.,7.ALPHA.)-3,7-DIHYDROXY-24-OXOCHOLAN-24-YL)-

Systematic Name

English

CHENODEOXYCHOLYLGLYCINE

Common Name

English

GLYCINE CHENODEOXYCHOLATE

Common Name

English

Classification Tree Code System Code

LOINC

2066-9