CIREVETMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 10:09:49 GMT 2025` Edited by `admin` on `Wed Apr 02 10:09:49 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG2
Sequence Origin	CANIS FAMILIARIS-MUS MUSCULUS
Sequence Type	COMPLETE
Record UNII	44Y3PDN3XY
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ZTS-00521426

Preferred Name

English

CIREVETMAB

Official Name

English

cirevetmab [INN]

Common Name

English

IMMUNOGLOBULIN G2 (237-ALANINE,238-ALANINE,240-ALANINE), ANTI-(CANIS FAMILIARIS TRANSFORMING GROWTH FACTOR .BETA.1) (CANIS FAMILIARIS-MUS MUSCULUS MONOCLONAL ZTS-00521426 .GAMMA.2-CHAIN), DISULFIDE WITH CANIS FAMILIARIS-MUS MUSCULUS MONOCLONAL ZTS-005214

Common Name

English

Code System Code Type Description

INN

11970

Created by admin on Wed Apr 02 10:09:49 GMT 2025 , Edited by admin on Wed Apr 02 10:09:49 GMT 2025

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FDA UNII

44Y3PDN3XY

Created by admin on Wed Apr 02 10:09:49 GMT 2025 , Edited by admin on Wed Apr 02 10:09:49 GMT 2025

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SMS_ID

300000036202

Created by admin on Wed Apr 02 10:09:49 GMT 2025 , Edited by admin on Wed Apr 02 10:09:49 GMT 2025

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CAS

2473240-98-9

Created by admin on Wed Apr 02 10:09:49 GMT 2025 , Edited by admin on Wed Apr 02 10:09:49 GMT 2025

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NCI_THESAURUS

C188512

Created by admin on Wed Apr 02 10:09:49 GMT 2025 , Edited by admin on Wed Apr 02 10:09:49 GMT 2025

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From	To
4_134	4_193
4_23	4_88
3_134	3_193
3_23	3_88
2_370	2_430
2_264	2_324
2_132	4_213
2_144	2_200
2_22	2_96
1_370	1_430
1_264	1_324
1_232	2_232
1_229	2_229
1_132	3_213
1_144	1_200
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					44Y3PDN3XY

ACTIVE MOIETY

Comments:

immunomodulator (veterinary use); anti-(Canis familiaris transforming growth factor ?1)

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_452] [2_452]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL