ER-36009

CC1(C)CCC(C)(C)C2=C1N=CC(=N2)C3=CSC(=N3)C4=CC=C(C=C4)C(O)=O

InChIKey=RLBKELXRLMNRJB-UHFFFAOYSA-N

InChI=1S/C22H23N3O2S/c1-21(2)9-10-22(3,4)18-17(21)23-11-15(24-18)16-12-28-19(25-16)13-5-7-14(8-6-13)20(26)27/h5-8,11-12H,9-10H2,1-4H3,(H,26,27)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Comedolytic effect of a novel RARgamma-specific retinoid, ER36009: comparison with retinoic acid in the rhino mouse model.	2005 Nov-Dec	16280299
Topical ER36009, a RARgamma-selective retinoid, decreases abdominal white adipose tissue and elicits changes in expression of genes related to adiposity and thermogenesis.	2006 Aug	17185799
Marked improvement induced in photoaged skin of hairless mouse by ER36009, a novel RARgamma-specific retinoid, but not by ER35794, an RXR-selective agonist.	2006 Nov	17076708

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:03:20 GMT 2023` Edited by `admin` on `Sat Dec 16 11:03:20 GMT 2023`
Record UNII	44X4BU4PFM
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

ER-36009

Common Name

English

BENZOIC ACID, 4-(4-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-QUINOXALINYL)-2-THIAZOLYL)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

10172878

Created by admin on Sat Dec 16 11:03:20 GMT 2023 , Edited by admin on Sat Dec 16 11:03:20 GMT 2023

PRIMARY

CAS

187400-31-3

Created by admin on Sat Dec 16 11:03:20 GMT 2023 , Edited by admin on Sat Dec 16 11:03:20 GMT 2023

PRIMARY

FDA UNII

44X4BU4PFM

Created by admin on Sat Dec 16 11:03:20 GMT 2023 , Edited by admin on Sat Dec 16 11:03:20 GMT 2023

PRIMARY

Related Record Type Details


					44X4BU4PFM

ER-36009

ACTIVE MOIETY