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Details

Stereochemistry ACHIRAL
Molecular Formula C22H23N3O2S
Molecular Weight 393.502
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ER-36009

SMILES

CC1(C)CCC(C)(C)C2=NC(=CN=C12)C3=CSC(=N3)C4=CC=C(C=C4)C(O)=O

InChI

InChIKey=RLBKELXRLMNRJB-UHFFFAOYSA-N
InChI=1S/C22H23N3O2S/c1-21(2)9-10-22(3,4)18-17(21)23-11-15(24-18)16-12-28-19(25-16)13-5-7-14(8-6-13)20(26)27/h5-8,11-12H,9-10H2,1-4H3,(H,26,27)

HIDE SMILES / InChI

Molecular Formula C22H23N3O2S
Molecular Weight 393.502
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Marked improvement induced in photoaged skin of hairless mouse by ER36009, a novel RARgamma-specific retinoid, but not by ER35794, an RXR-selective agonist.
2006-11
Topical ER36009, a RARgamma-selective retinoid, decreases abdominal white adipose tissue and elicits changes in expression of genes related to adiposity and thermogenesis.
2006-08
Comedolytic effect of a novel RARgamma-specific retinoid, ER36009: comparison with retinoic acid in the rhino mouse model.
2005-08-23
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 23:36:09 GMT 2025
Edited
by admin
on Mon Mar 31 23:36:09 GMT 2025
Record UNII
44X4BU4PFM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BENZOIC ACID, 4-(4-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-QUINOXALINYL)-2-THIAZOLYL)-
Preferred Name English
ER-36009
Common Name English
Code System Code Type Description
PUBCHEM
10172878
Created by admin on Mon Mar 31 23:36:09 GMT 2025 , Edited by admin on Mon Mar 31 23:36:09 GMT 2025
PRIMARY
CAS
187400-31-3
Created by admin on Mon Mar 31 23:36:09 GMT 2025 , Edited by admin on Mon Mar 31 23:36:09 GMT 2025
PRIMARY
FDA UNII
44X4BU4PFM
Created by admin on Mon Mar 31 23:36:09 GMT 2025 , Edited by admin on Mon Mar 31 23:36:09 GMT 2025
PRIMARY
Related Record Type Details
ACTIVE MOIETY