TAMETRALINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C17H19N
Molecular Weight	237.3395
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN[C@@H]1CC[C@@H](C2=CC=CC=C2)C3=C1C=CC=C3

InChI

InChIKey=NVXPZMLRGBVYQV-WMLDXEAASA-N

InChI=1S/C17H19N/c1-18-17-12-11-14(13-7-3-2-4-8-13)15-9-5-6-10-16(15)17/h2-10,14,17-18H,11-12H2,1H3/t14-,17+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C17H19N
Molecular Weight	237.3395
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6492080 | https://www.genome.jp/dbget-bin/www_bget?drug+D02703

Tametraline (also known as CP-24,441) is a norepinephrine-dopamine reuptake inhibitor that was developed as an Antidepressant agent. Information about the current use of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain.	1976 Dec	994022
Nontricyclic antidepressant agents derived from cis- and trans-1-amino-4-aryltetralins.	1984 Nov	6492080

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:58:30 GMT 2023` Edited by `admin` on `Fri Dec 15 15:58:30 GMT 2023`
Record UNII	440C8K5Y5K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TAMETRALINE

Official Name

English

(1R,4S)-N-METHYL-4-PHENYL-1,2,3,4-TETRAHYDRONAPHTHALEN-1-AMINE

Systematic Name

English

CP-24,441

Code

English

CP-24441

Code

English

tametraline [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265