6-METHOXYHARMALAN

COC1=CC2=C(NC3=C2CCN=C3C)C=C1

InChIKey=HMBHRMFLDKKSCT-UHFFFAOYSA-N

InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Serotonin 2c (5-HT2c) receptor 131 Target ID: CHEMBL225 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14643338	Binding Agent 1076	924.0 nM [Ki]
Serotonin 6 (5-HT6) receptor 44 Target ID: CHEMBL3371 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14643338	Binding Agent 1076	1930.0 nM [Ki]
Serotonin 7 (5-HT7) receptor 30 Target ID: CHEMBL3155 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14643338	Binding Agent 1076	2960.0 nM [Ki]

PubMed

Title	Date	PubMed
Phytochemical and pharmacological study of roots and leaves of Guiera senegalensis J.F. Gmel (Combretaceae).	2006-06-30	16443341
Harmane and harmalan are bioactive components of classical clonidine-displacing substance.	2004-12-28	15610033

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:20:37 GMT 2025` Edited by `admin` on `Mon Mar 31 21:20:37 GMT 2025`
Record UNII	43F45VJV8C
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

6-METHOXYHARMALAN

Common Name

English

1-METHYL-6-METHOXY-3,4-DIHYDRO-2-CARBOLINE

Preferred Name

English

6-METHOXYHARMALANE

Common Name

English

1-METHYL-6-METHOXY-DIHYDRO-.BETA.-CARBOLINE

Systematic Name

English

10-METHOXYHARMALAN [MI]

Common Name

English

3,4-DIHYDROMETHOXYHARMAN

Common Name

English

4,9-DIHYDRO-6-METHOXY-1-METHYL-3H-PYRIDO(3,4-B)INDOLE

Systematic Name

English

Code System Code Type Description

CAS

3589-73-9