NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 3

Approval Year

Substance Class	Protein
Protein Type	RECEPTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	438XLITDI3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 3

Common Name

English

CAR

Preferred Name

English

CONSTITUTIVE ACTIVATOR OF RETINOID RESPONSE

Common Name

English

NR1I3

Common Name

English

CONSTITUTIVE ANDROSTANE RECEPTOR

Common Name

English

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Code System

Code

Type

Description

FDA UNII

438XLITDI3

PRIMARY

Showing 1 to 1 of 1 entries

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Subunit 0

Linkage Type	Residue Index
COORDINATION COMPOUND	1_47	1_53	1_63	1_66
COORDINATION COMPOUND	1_11	1_14	1_28	1_31

Related Record Type Details


					0GEI24LG0J

CHENODIOL

AGONIST -> TARGET

Interaction Type:

INHIBITOR

Qualification:

EC50

Amount:

6.6 MICROMOLAR (average)


					459AG36T1B

PRASTERONE

ACTIVATOR -> TARGET

Interaction Type:

ACTIVATOR

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_11] [1_14] [1_28] [1_31]	SITE_SPECIFIC	C4-TYPE ZINC FINGER	C56TF4V7OP
AMINO ACID SUBSTITUTION	[1_38]		THREONINE PHOSPHATE	3L4WX7B1EI
AMINO_ACID_SUBSTITUTION	[1_47] [1_53] [1_63] [1_66]	SITE_SPECIFIC	C4-TYPE ZINC FINGER	C56TF4V7OP

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL