ISOBARBITURIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H4N2O3
Molecular Weight	128.0862
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C1NCC(=O)C(=O)N1

InChI

InChIKey=FQXOOGHQVPKHPG-UHFFFAOYSA-N

InChI=1S/C4H4N2O3/c7-2-1-5-4(9)6-3(2)8/h1H2,(H2,5,6,8,9)

HIDE SMILES / InChI

Molecular Formula	C4H4N2O3
Molecular Weight	128.0862
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Stimulation of human endonuclease III by Y box-binding protein 1 (DNA-binding protein B). Interaction between a base excision repair enzyme and a transcription factor.	2001 Jun 15	11287425
A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue.	2002 Nov 1	12200441
Detection of p53 mutations in precancerous gastric tissue.	2003 Oct 6	14520466
Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases.	2003 Sep 5	12819227
Reaction of substituted pyrimidines with photochemically generated t-BuO* radicals.	2005 Dec	16955740
Differential modulation of base excision repair activities during brain ontogeny: implications for repair of transcribed DNA.	2006 Jan	16257035
DNA oxidation in Alzheimer's disease.	2006 Nov-Dec	17034348
Base-pairing properties of the oxidized cytosine derivative, 5-hydroxy uracil.	2008 Feb 15	18078807
Interaction of the human DNA glycosylase NEIL1 with proliferating cell nuclear antigen. The potential for replication-associated repair of oxidized bases in mammalian genomes.	2008 Feb 8	18032376
Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors.	2009 Mar 5	19265512
Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair.	2010 Dec 16	21209706
Substrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases.	2010 Jun 4	20346739
Early Steps in the DNA Base Excision Repair Pathway of a Fission Yeast Schizosaccharomyces pombe.	2010 Sep 16	20936170

Substance Class	Chemical Created by `admin` on `Sat Dec 16 00:42:07 UTC 2023` Edited by `admin` on `Sat Dec 16 00:42:07 UTC 2023`
Record UNII	438WJI1S49
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ISOBARBITURIC ACID

Common Name

English

5-HYDROXY-2,4(1H,3H)-PYRIMIDINEDIONE

Systematic Name

English

FLUOROURACIL RELATED COMPOUND B [USP IMPURITY]

Common Name

English

DIHYDROPYRIMIDINE-2,4,5(3H)-TRIONE

Systematic Name

English

NSC-90431

Code

English

2,4(1H,3H)-PYRIMIDINEDIONE, 5-HYDROXY-

Systematic Name

English

2,4,5(3H)-PYRIMIDINETRIONE, DIHYDRO-

Systematic Name

English

5-HYDROXYURACIL

Systematic Name

English

FLUOROURACIL RELATED COMPOUND B [USP-RS]

Common Name

English

FLUOROURACIL IMPURITY B [EP IMPURITY]

Common Name

English

NSC-95958

Code

English

Code System Code Type Description

EPA CompTox

DTXSID30174667