Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C5H8O4 |
| Molecular Weight | 132.1146 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCC(C(O)=O)C(O)=O
InChI
InChIKey=UKFXDFUAPNAMPJ-UHFFFAOYSA-N
InChI=1S/C5H8O4/c1-2-3(4(6)7)5(8)9/h3H,2H2,1H3,(H,6,7)(H,8,9)
| Molecular Formula | C5H8O4 |
| Molecular Weight | 132.1146 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Risk factors of ocular involvement in children with mitochondrial respiratory chain complex defect. | 2010-12 |
|
| Ethylene glycol monomethyl ether-induced toxicity is mediated through the inhibition of flavoprotein dehydrogenase enzyme family. | 2010-12 |
|
| A systems biology approach uncovers cellular strategies used by Methylobacterium extorquens AM1 during the switch from multi- to single-carbon growth. | 2010-11-24 |
|
| 6-[Bis(ethoxycarbonyl)methyl]-6-deoxy-1,2;3,4-di-O-isopropyl-idene-d-galacto-pyran-ose. | 2010-11-17 |
|
| Pathogenesis and treatment of mitochondrial myopathies: recent advances. | 2010-10 |
|
| Clinical aspects of short-chain acyl-CoA dehydrogenase deficiency. | 2010-10 |
|
| Combined treatment with oral metronidazole and N-acetylcysteine is effective in ethylmalonic encephalopathy. | 2010-08 |
|
| Antioxidant dysfunction: potential risk for neurotoxicity in ethylmalonic aciduria. | 2010-06 |
|
| Silent increase of urinary ethylmalonic acid is an indicator of nonspecific brain dysfunction. | 2010-05 |
|
| Flavin adenine dinucleotide status and the effects of high-dose riboflavin treatment in short-chain acyl-CoA dehydrogenase deficiency. | 2010-03 |
|
| Promotion of lipid and protein oxidative damage in rat brain by ethylmalonic acid. | 2010-02 |
|
| Fasting and fat-loading tests provide pathophysiological insight into short-chain acyl-coenzyme a dehydrogenase deficiency. | 2010-01 |
|
| Inborn errors of energy metabolism associated with myopathies. | 2010 |
|
| Chronic early postnatal administration of ethylmalonic acid to rats causes behavioral deficit. | 2009-02-11 |
|
| Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy. | 2009-02 |
|
| Short-chain acyl-coenzyme A dehydrogenase deficiency. | 2008-12 |
|
| The ACADS gene variation spectrum in 114 patients with short-chain acyl-CoA dehydrogenase (SCAD) deficiency is dominated by missense variations leading to protein misfolding at the cellular level. | 2008-08 |
|
| [Short-chain acyl-CoA dehydrogenase deficiency (SCADD): relatively high prevalence in the Netherlands and strongly variable fenotype; neonatal screening not indicated]. | 2008-07-26 |
|
| 2-(4-Ethoxy-benzyl-idene)butanoic acid. | 2008-07-12 |
|
| Severe infantile hypotonia with ethylmalonic aciduria: case report. | 2008-06 |
|
| Acquired multiple Acyl-CoA dehydrogenase deficiency in 10 horses with atypical myopathy. | 2008-05 |
|
| (E)-2-(2-Fluoro-benzyl-idene)butanoic acid. | 2008-03-20 |
|
| A new case of short-chain acyl-CoA dehydrogenase deficiency: clinical, biochemical, genetic and (1)H-NMR spectroscopic studies. | 2007-12 |
|
| Equine biochemical multiple acyl-CoA dehydrogenase deficiency (MADD) as a cause of rhabdomyolysis. | 2007-08 |
|
| Ethylmalonic encephalopathy: clinical and biochemical observations. | 2007-04 |
|
| Lessons to learn from rare inborn errors of metabolism. | 2007-04 |
|
| Development of a newborn screening follow-up algorithm for the diagnosis of isobutyryl-CoA dehydrogenase deficiency. | 2007-02 |
|
| Taxonomic revision of Aspergillus section Clavati based on molecular, morphological and physiological data. | 2007 |
|
| Single-nucleotide variations in the genes encoding the mitochondrial Hsp60/Hsp10 chaperone system and their disease-causing potential. | 2007 |
|
| A case of ethylmalonic encephalopathy with atypical clinical and biochemical presentation. | 2006-12 |
|
| Persistent increase of plasma butyryl/isobutyrylcarnitine concentrations as marker of SCAD defect and ethylmalonic encephalopathy. | 2006-10 |
|
| Clinical, biochemical, and genetic heterogeneity in short-chain acyl-coenzyme A dehydrogenase deficiency. | 2006-08-23 |
|
| Ethylmalonic encephalopathy-report of two cases. | 2006-06 |
|
| ETHE1 mutations are specific to ethylmalonic encephalopathy. | 2006-04 |
|
| Effect of in vivo administration of ethylmalonic acid on energy metabolism in rat tissues. | 2006-03 |
|
| Inhibition of the electron transport chain and creatine kinase activity by ethylmalonic acid in human skeletal muscle. | 2006-03 |
|
| Metabolomic and bioinformatic analyses in asphyxiated neonates. | 2006-03 |
|
| Perioperative management of a child with short-chain acyl-CoA dehydrogenase deficiency. | 2005-09 |
|
| Acyl-CoA dehydrogenase deficiency: varieties with neurological involvement. | 2005-03 |
|
| Clinical, biochemical, magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (1H MRS) findings in a fourth case of combined D- and L-2 hydroxyglutaric aciduria. | 2005 |
|
| The putative elaiophylin biosynthetic gene cluster in Streptomyces sp. DSM4137 is adjacent to genes encoding adenosylcobalamin-dependent methylmalonyl CoA mutase and to genes for synthesis of cobalamin. | 2004-09-30 |
|
| Recent developments and new applications of tandem mass spectrometry in newborn screening. | 2004-08 |
|
| The role of methionine in ethylmalonic encephalopathy with petechiae. | 2004-04 |
|
| Ethylmalonic encephalopathy is caused by mutations in ETHE1, a gene encoding a mitochondrial matrix protein. | 2004-02 |
|
| [Late-onset riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency (glutaric aciduria type II)]. | 2003-12 |
|
| Short-chain Acyl-CoA dehydrogenase deficiency: studies in a large family adding to the complexity of the disorder. | 2003-11 |
|
| A comparison of in vitro acylcarnitine profiling methods for the diagnosis of classical and variant short chain acyl-CoA dehydrogenase deficiency. | 2003-11 |
|
| Mutation analysis of copper transporter genes in patients with ethylmalonic encephalopathy, mitochondriopathies and copper deficiency phenotypes. | 2003 |
|
| Clinical and biochemical characterization of short-chain acyl-coenzyme A dehydrogenase deficiency. | 1995-06 |
|
| Age-related reference values for urinary organic acids in a healthy Turkish pediatric population. | 1994-06 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:54:53 GMT 2025
by
admin
on
Mon Mar 31 19:54:53 GMT 2025
|
| Record UNII |
432NF49DFG
|
| Record Status |
Validated (UNII)
|
| Record Version |
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210-007-2
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432NF49DFG
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DTXSID00208842
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601-75-2
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96615
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C038080
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11756
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