Livmoniplimab

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 23:53:56 GMT 2025` Edited by `admin` on `Tue Apr 01 23:53:56 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	42SH7JCD82
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ABBV-151

Preferred Name

English

Livmoniplimab

Official Name

English

Immunoglobulin G4 [234-proline], anti-(human protein GARP-transforming growth factor ?1 complex) (human monoclonal ABBV-151 ?4-chain), disulfide with human monoclonal ABBV-151 ?-chain, dimer

Common Name

English

Immunoglobulin G4-kappa, anti-[Homo sapiens LRRC32 (leucine rich repeat containing 32, transforming growth factor beta activator LRRC32, glycoprotein A repetitions predominant, GARP) / Homo sapiens TGFB1 (transforming growth factor beta1, TGF beta) compl

Common Name

English

livmoniplimab [INN]

Common Name

English

ABBV151

Code

English

ARGX-115

Code

English

PR-1762844

Code

English

Livmoniplimab [WHO-DD]

Common Name

English

LIVMONIPLIMAB [USAN]

Common Name

English

Code System Code Type Description

INN

11741

Created by admin on Tue Apr 01 23:53:56 GMT 2025 , Edited by admin on Tue Apr 01 23:53:56 GMT 2025

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SMS_ID

300000013020

Created by admin on Tue Apr 01 23:53:56 GMT 2025 , Edited by admin on Tue Apr 01 23:53:56 GMT 2025

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CAS

2412004-88-5

Created by admin on Tue Apr 01 23:53:56 GMT 2025 , Edited by admin on Tue Apr 01 23:53:56 GMT 2025

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FDA UNII

42SH7JCD82

Created by admin on Tue Apr 01 23:53:56 GMT 2025 , Edited by admin on Tue Apr 01 23:53:56 GMT 2025

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USAN

LM-234

Created by admin on Tue Apr 01 23:53:56 GMT 2025 , Edited by admin on Tue Apr 01 23:53:56 GMT 2025

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NCI_THESAURUS

C165684

Created by admin on Tue Apr 01 23:53:56 GMT 2025 , Edited by admin on Tue Apr 01 23:53:56 GMT 2025

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From	To
1_22	1_96
2_22	2_96
2_140	4_214
2_153	2_209
2_267	2_327
1_140	3_214
2_373	2_431
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_153	1_209
1_232	2_232
1_235	2_235
1_267	1_327
1_373	1_431

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_303
N	2_303

Related Record Type Details


					C9AJ102J44

CYCLIC NUCLEOTIDE-GATED CATION CHANNEL BETA-1

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					42SH7JCD82

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL