Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C3H6O3 |
| Molecular Weight | 90.0779 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC[C@@H](O)C=O
InChI
InChIKey=MNQZXJOMYWMBOU-VKHMYHEASA-N
InChI=1S/C3H6O3/c4-1-3(6)2-5/h1,3,5-6H,2H2/t3-/m0/s1
| Molecular Formula | C3H6O3 |
| Molecular Weight | 90.0779 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: GO:0030073 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15213233 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Molecular and biochemical characterisation of human short-chain dehydrogenase/reductase member 3 (DHRS3). | 2015-06-05 |
|
| Triphenyltin impairs insulin secretion by decreasing glucose-induced NADP(H) and ATP production in hamster pancreatic β-cells. | 2012-09-28 |
|
| Cytotoxic molecular mechanisms and cytoprotection by enzymic metabolism or autoxidation for glyceraldehyde, hydroxypyruvate and glycolaldehyde. | 2011-05-30 |
|
| Functional expression of novel human and murine AKR1B genes. | 2011-05-30 |
|
| Hepatocyte or serum albumin protein carbonylation by oxidized fructose metabolites: Glyceraldehyde or glycolaldehyde as endogenous toxins? | 2010-10-06 |
|
| Synthesis of sialoglycopolypeptide for potentially blocking influenza virus infection using a rat alpha2,6-sialyltransferase expressed in BmNPV bacmid-injected silkworm larvae. | 2009-06-05 |
|
| Cancer biomarker AKR1B10 and carbonyl metabolism. | 2009-03-16 |
|
| Aldo-keto reductases from the AKR1B subfamily: retinoid specificity and control of cellular retinoic acid levels. | 2009-03-16 |
|
| Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers. | 2008-04-28 |
|
| Reduced 293T cell susceptibility to acrolein due to aldose reductase-like-1 protein expression. | 2007-06 |
|
| Aldehydes release zinc from proteins. A pathway from oxidative stress/lipid peroxidation to cellular functions of zinc. | 2006-09 |
|
| Stimulation of insulin release by glyceraldehyde may not be similar to glucose. | 2006-03-15 |
|
| Structure of the thermolabile mutant aldolase B, A149P: molecular basis of hereditary fructose intolerance. | 2005-03-18 |
|
| Serum or cerebrospinal fluid levels of glyceraldehyde-derived advanced glycation end products (AGEs) may be a promising biomarker for early detection of Alzheimer's disease. | 2005 |
|
| Glyceraldehyde-derived advanced glycation end products in Alzheimer's disease. | 2004-09 |
|
| Effect of carbonyl compounds on red blood cells deformability. | 2004-08-27 |
|
| 8-Hydroxydaidzein, an aldose reductase inhibitor from okara fermented with Aspergillus sp. HK-388. | 2004-07 |
|
| Alternative routes for the formation of glyceraldehyde-derived AGEs (TAGE) in vivo. | 2004 |
|
| Metabolism, not autoxidation, plays a role in alpha-oxoaldehyde- and reducing sugar-induced erythrocyte GSH depletion: relevance for diabetes mellitus. | 2003-10 |
|
| Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification. | 2003-09-16 |
|
| A flavone from Manilkara indica as a specific inhibitor against aldose reductase in vitro. | 2003-09 |
|
| A practical method to study functional impairment of proteins by glycation and effects of inhibitors using current coagulation/fibrinolysis reagent kits. | 2003-03 |
|
| Low molecular organic inactivators in differentiating organ origin of alpha-amylase in humans. Part I. | 1989-10-01 |
|
| Urine glyceraldehyde excretion is elevated in the renal Fanconi syndrome. | 1989-01 |
|
| Re-evaluation of the fructosamine reaction. | 1988-08 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:45:59 GMT 2025
by
admin
on
Mon Mar 31 22:45:59 GMT 2025
|
| Record UNII |
41A680M0WB
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Preferred Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
41A680M0WB
Created by
admin on Mon Mar 31 22:45:59 GMT 2025 , Edited by admin on Mon Mar 31 22:45:59 GMT 2025
|
PRIMARY | |||
|
DTXSID70196464
Created by
admin on Mon Mar 31 22:45:59 GMT 2025 , Edited by admin on Mon Mar 31 22:45:59 GMT 2025
|
PRIMARY | |||
|
17378
Created by
admin on Mon Mar 31 22:45:59 GMT 2025 , Edited by admin on Mon Mar 31 22:45:59 GMT 2025
|
PRIMARY | |||
|
79014
Created by
admin on Mon Mar 31 22:45:59 GMT 2025 , Edited by admin on Mon Mar 31 22:45:59 GMT 2025
|
PRIMARY | |||
|
207-217-1
Created by
admin on Mon Mar 31 22:45:59 GMT 2025 , Edited by admin on Mon Mar 31 22:45:59 GMT 2025
|
PRIMARY | |||
|
m5787
Created by
admin on Mon Mar 31 22:45:59 GMT 2025 , Edited by admin on Mon Mar 31 22:45:59 GMT 2025
|
PRIMARY | Merck Index | ||
|
DB02536
Created by
admin on Mon Mar 31 22:45:59 GMT 2025 , Edited by admin on Mon Mar 31 22:45:59 GMT 2025
|
PRIMARY | |||
|
453-17-8
Created by
admin on Mon Mar 31 22:45:59 GMT 2025 , Edited by admin on Mon Mar 31 22:45:59 GMT 2025
|
PRIMARY | |||
|
27137
Created by
admin on Mon Mar 31 22:45:59 GMT 2025 , Edited by admin on Mon Mar 31 22:45:59 GMT 2025
|
PRIMARY | |||
|
91534
Created by
admin on Mon Mar 31 22:45:59 GMT 2025 , Edited by admin on Mon Mar 31 22:45:59 GMT 2025
|
PRIMARY |