TIAFIBRATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C34H48Cl2O6S2
Molecular Weight	687.777
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(OC1=CC=C(Cl)C=C1)C(=O)OCCSCCCCCCCCCCSCCOC(=O)C(C)(C)OC2=CC=C(Cl)C=C2

InChI

InChIKey=RSLQBRWTDJTEHT-UHFFFAOYSA-N

InChI=1S/C34H48Cl2O6S2/c1-33(2,41-29-17-13-27(35)14-18-29)31(37)39-21-25-43-23-11-9-7-5-6-8-10-12-24-44-26-22-40-32(38)34(3,4)42-30-19-15-28(36)16-20-30/h13-20H,5-12,21-26H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C34H48Cl2O6S2
Molecular Weight	687.777
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19770217&CC=DE&NR=2547572B1&KC=B1 | https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19770216&CC=ES&NR=438996A1&KC=A1

Tiafibrate is a dithiahexadecanediol derivative patented by Juste S. A. Quimico-Farmaceutica as a hypocholesteremic agent. In rats, Tiafibrate at 125 mg/kg day orally for 14 days gave a 38.8% decrease in blood lipids and a 33.7% decrease in blood cholesterol.

Originator

Approval Year

Patents

Sample Use Guides

In Vivo Use Guide

125 mg/kg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:22:36 GMT 2023` Edited by `admin` on `Sat Dec 16 17:22:36 GMT 2023`
Record UNII	41729970BE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TIAFIBRATE

Official Name

English

2-(P-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID DIESTER WITH 2,2'-(DECAMETHYLENEDITHIO)DIETHANOL

Common Name

English

tiafibrate [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C98150