Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C29H35N11O11S |
| Molecular Weight | 745.72 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
N[C@@H](CNC(=O)CC[C@@H](NC(=O)C1=CC=C(NCC2=CNC3=NC(N)=NC(=O)C3=N2)C=C1)C(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CS)C(O)=O
InChI
InChIKey=RKGPQAGUQDVJHG-MHORFTMASA-N
InChI=1S/C29H35N11O11S/c30-15(24(45)37-17(7-20(42)43)25(46)38-18(11-52)28(50)51)10-33-19(41)6-5-16(27(48)49)36-23(44)12-1-3-13(4-2-12)32-8-14-9-34-22-21(35-14)26(47)40-29(31)39-22/h1-4,9,15-18,32,52H,5-8,10-11,30H2,(H,33,41)(H,36,44)(H,37,45)(H,38,46)(H,42,43)(H,48,49)(H,50,51)(H3,31,34,39,40,47)/t15-,16+,17-,18-/m0/s1
| Molecular Formula | C29H35N11O11S |
| Molecular Weight | 745.72 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Etarfolatide (EC20) is a conjugate of folic acid and peptidic metal-chelating moiety. Technetium Tc99m radiolabeled etarfolatide is a folate-targeted molecular imaging agent that is being developed to non-invasively identify tumors that express folate receptors and that may respond to folate-targeted therapy. It is being co-developed as the companion imaging agent to Vynfinit® (vintafolide) and EC1456 (folate-tubulysin).
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 02:22:22 GMT 2023
by
admin
on
Sat Dec 16 02:22:22 GMT 2023
|
| Record UNII |
40UB1H6Q6T
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Common Name | English | ||
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Code | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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FDA ORPHAN DRUG |
131399
Created by
admin on Sat Dec 16 02:22:22 GMT 2023 , Edited by admin on Sat Dec 16 02:22:22 GMT 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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479578-27-3
Created by
admin on Sat Dec 16 02:22:22 GMT 2023 , Edited by admin on Sat Dec 16 02:22:22 GMT 2023
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SUB91724
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40UB1H6Q6T
Created by
admin on Sat Dec 16 02:22:22 GMT 2023 , Edited by admin on Sat Dec 16 02:22:22 GMT 2023
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DB11810
Created by
admin on Sat Dec 16 02:22:22 GMT 2023 , Edited by admin on Sat Dec 16 02:22:22 GMT 2023
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Etarfolatide
Created by
admin on Sat Dec 16 02:22:22 GMT 2023 , Edited by admin on Sat Dec 16 02:22:22 GMT 2023
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DTXSID40197367
Created by
admin on Sat Dec 16 02:22:22 GMT 2023 , Edited by admin on Sat Dec 16 02:22:22 GMT 2023
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100000141353
Created by
admin on Sat Dec 16 02:22:22 GMT 2023 , Edited by admin on Sat Dec 16 02:22:22 GMT 2023
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135428923
Created by
admin on Sat Dec 16 02:22:22 GMT 2023 , Edited by admin on Sat Dec 16 02:22:22 GMT 2023
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| Related Record | Type | Details | ||
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LABELED -> NON-LABELED |
