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Details

Stereochemistry ACHIRAL
Molecular Formula C10F20
Molecular Weight 500.0751
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PERFLUORO TERT-BUTYLCYCLOHEXANE

SMILES

FC(F)(F)C(C(F)(F)F)(C(F)(F)F)C1(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C1(F)F

InChI

InChIKey=VLTXBOGHSBHSAC-UHFFFAOYSA-N
InChI=1S/C10F20/c11-2(1(8(22,23)24,9(25,26)27)10(28,29)30)3(12,13)5(16,17)7(20,21)6(18,19)4(2,14)15

HIDE SMILES / InChI

Molecular Formula C10F20
Molecular Weight 500.0751
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Perfluoro tert-butylcyclohexane (PTBCH) is a perfluorocarbon emulsion that acts as a highly effective oxygen carrier compared to blood. Administration of PTBCH significantly increased parenchymal tissue oxygen levels during the usual post-injury hypoxic phase, and PTBCH has been shown to be effective in stroke and head injury. Administration of PTBCH during cardiopulmonary bypass was associated with an excessive release of cytokines. This enhanced inflammatory response with subsequent hypotension may have contributed to mortality in rats receiving PTBCH. The observed patterns of myocardial injury indicate global hypoperfusion and catecholamine excess.

Approval Year

PubMed

Substance Class Chemical
Record UNII
3ZX1Z33VUU
Record Status Validated (UNII)
Record Version