ATROPINE OXIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H23NO4
Molecular Weight	305.3688
Optical Activity	( + / - )
Defined Stereocenters	3 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[N@+]1([O-])[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)C3=CC=CC=C3

InChI

InChIKey=HGWPFSBHDACWNL-LZYIFBDPSA-N

InChI=1S/C17H23NO4/c1-18(21)13-7-8-14(18)10-15(9-13)22-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?,18?

HIDE SMILES / InChI

Molecular Formula	C17H23NO4
Molecular Weight	305.3688
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	2 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: http://www.genome.jp/dbget-bin/www_bget?dr:D03011 | https://edkb.fda.gov/webstart/arraytrack/PDFfile/LTKB_BD/atropine.pdf

Atropine-N-oxide hydrochloride is an alkaloid of the belladonna plants. It is the major metabolite of atropine. It is a competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Muscarinic acetylcholine receptor 160 Target ID: CHEMBL2094109 Sources: http://www.genome.jp/dbget-bin/www_bget?dr:D03011	Antagonist 2778

Conditions

Condition	Modality	Targets	Highest Phase	Product
Ophthalmic disorder 2 Sources: https://www.google.com/patents/US9421199	Primary		Basic research	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
The metabolism of atropine in man.	1986 Oct	2879005

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:55:28 GMT 2023` Edited by `admin` on `Sat Dec 16 16:55:28 GMT 2023`
Record UNII	3Y03IC177D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ATROPINE OXIDE

Official Name

English

ATROPINE N-OXIDE [MI]

Common Name

English

BENZENEACETIC ACID, .ALPHA.-(HYDROXYMETHYL)-8-METHYL-8-AZABICYCLO(3.2.1)OCT-3-YL ESTER, 8-OXIDE, ENDO-(±)-

Common Name

English

ATROPINE AMINOXIDE

Common Name

English

APITROPIN

Brand Name

English

AMINOXYTROPINE TROPATE

Common Name

English

atropine oxide [INN]

Common Name

English

1.ALPHA.H,5.ALPHA.H-TROPAN-3.ALPHA.-OL (±)-TROPATE(ESTER) 8-OXIDE

Common Name

English

NSC-72861

Code

English

GENATROPINE

Common Name

English

ATROPINE N-OXIDE

Common Name

English

Code System Code Type Description

DRUG CENTRAL

261