ATROPINE OXIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H23NO4
Molecular Weight	305.3688
Optical Activity	( + / - )
Defined Stereocenters	3 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[N@+]1([O-])[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)C3=CC=CC=C3

InChI

InChIKey=HGWPFSBHDACWNL-LZYIFBDPSA-N

InChI=1S/C17H23NO4/c1-18(21)13-7-8-14(18)10-15(9-13)22-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?,18?

HIDE SMILES / InChI

Molecular Formula	C17H23NO4
Molecular Weight	305.3688
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	2 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: http://www.genome.jp/dbget-bin/www_bget?dr:D03011 | https://edkb.fda.gov/webstart/arraytrack/PDFfile/LTKB_BD/atropine.pdf

Atropine-N-oxide hydrochloride is an alkaloid of the belladonna plants. It is the major metabolite of atropine. It is a competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Muscarinic acetylcholine receptor 160 Target ID: CHEMBL2094109 Sources: http://www.genome.jp/dbget-bin/www_bget?dr:D03011	Antagonist 2778

Conditions

Condition	Modality	Targets	Highest Phase	Product
Ophthalmic disorder 2 Sources: https://www.google.com/patents/US9421199	Primary		Basic research	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:55:28 UTC 2023` Edited by `admin` on `Sat Dec 16 16:55:28 UTC 2023`
Record UNII	3Y03IC177D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ATROPINE OXIDE

Official Name

English

ATROPINE N-OXIDE [MI]

Common Name

English

BENZENEACETIC ACID, .ALPHA.-(HYDROXYMETHYL)-8-METHYL-8-AZABICYCLO(3.2.1)OCT-3-YL ESTER, 8-OXIDE, ENDO-(±)-

Common Name

English

ATROPINE AMINOXIDE

Common Name

English

APITROPIN

Brand Name

English

AMINOXYTROPINE TROPATE

Common Name

English

atropine oxide [INN]

Common Name

English

1.ALPHA.H,5.ALPHA.H-TROPAN-3.ALPHA.-OL (±)-TROPATE(ESTER) 8-OXIDE

Common Name

English

NSC-72861

Code

English

GENATROPINE

Common Name

English

ATROPINE N-OXIDE

Common Name

English

Code System Code Type Description

DRUG CENTRAL

261