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Details

Stereochemistry RACEMIC
Molecular Formula C17H23NO4
Molecular Weight 305.3695
Optical Activity ( + / - )
Defined Stereocenters 2 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ATROPINE OXIDE

SMILES

CN1(=O)[C@@]2([H])CC[C@]1([H])C[C@@]([H])(C2)OC(=O)C([H])(CO)c3ccccc3

InChI

InChIKey=HGWPFSBHDACWNL-LZYIFBDPSA-N
InChI=1S/C17H23NO4/c1-18(21)13-7-8-14(18)10-15(9-13)22-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?,18?

HIDE SMILES / InChI

Molecular Formula C17H23NO4
Molecular Weight 305.3695
Charge 0
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 2 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Atropine-N-oxide hydrochloride is an alkaloid of the belladonna plants. It is the major metabolite of atropine. It is a competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Originator

Curator's Comment:: Atropine was first obtained from the deadly nightshade (Atropa belladonna) by M. Brandes in 1819.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
The metabolism of atropine in man.
1986 Oct
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Jun 26 12:01:00 UTC 2021
Edited
by admin
on Sat Jun 26 12:01:00 UTC 2021
Record UNII
3Y03IC177D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ATROPINE OXIDE
INN  
INN  
Official Name English
ATROPINE N-OXIDE [MI]
Common Name English
BENZENEACETIC ACID, .ALPHA.-(HYDROXYMETHYL)-8-METHYL-8-AZABICYCLO(3.2.1)OCT-3-YL ESTER, 8-OXIDE, ENDO-(+/-)-
Common Name English
ATROPINE AMINOXIDE
Common Name English
APITROPIN
Brand Name English
AMINOXYTROPINE TROPATE
Common Name English
ATROPINE OXIDE [INN]
Common Name English
1.ALPHA.H,5.ALPHA.H-TROPAN-3.ALPHA.-OL (+/-)-TROPATE(ESTER) 8-OXIDE
Common Name English
NSC-72861
Code English
GENATROPINE
Common Name English
ATROPINE N-OXIDE
MI  
Common Name English
Code System Code Type Description
DRUG CENTRAL
261
Created by admin on Sat Jun 26 12:01:00 UTC 2021 , Edited by admin on Sat Jun 26 12:01:00 UTC 2021
PRIMARY
FDA UNII
3Y03IC177D
Created by admin on Sat Jun 26 12:01:00 UTC 2021 , Edited by admin on Sat Jun 26 12:01:00 UTC 2021
PRIMARY
MERCK INDEX
M2136
Created by admin on Sat Jun 26 12:01:00 UTC 2021 , Edited by admin on Sat Jun 26 12:01:00 UTC 2021
PRIMARY Merck Index
NCI_THESAURUS
C166707
Created by admin on Sat Jun 26 12:01:00 UTC 2021 , Edited by admin on Sat Jun 26 12:01:00 UTC 2021
PRIMARY
EPA CompTox
4438-22-6
Created by admin on Sat Jun 26 12:01:00 UTC 2021 , Edited by admin on Sat Jun 26 12:01:00 UTC 2021
PRIMARY
EVMPD
SUB05609MIG
Created by admin on Sat Jun 26 12:01:00 UTC 2021 , Edited by admin on Sat Jun 26 12:01:00 UTC 2021
PRIMARY
INN
1297
Created by admin on Sat Jun 26 12:01:00 UTC 2021 , Edited by admin on Sat Jun 26 12:01:00 UTC 2021
PRIMARY
ChEMBL
CHEMBL2146145
Created by admin on Sat Jun 26 12:01:00 UTC 2021 , Edited by admin on Sat Jun 26 12:01:00 UTC 2021
PRIMARY
CAS
4438-22-6
Created by admin on Sat Jun 26 12:01:00 UTC 2021 , Edited by admin on Sat Jun 26 12:01:00 UTC 2021
PRIMARY
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