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Details

Stereochemistry RACEMIC
Molecular Formula C4H10O2
Molecular Weight 90.121
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BUTYLENE GLYCOL

SMILES

CC(O)CCO

InChI

InChIKey=PUPZLCDOIYMWBV-UHFFFAOYSA-N
InChI=1S/C4H10O2/c1-4(6)2-3-5/h4-6H,2-3H2,1H3

HIDE SMILES / InChI

Molecular Formula C4H10O2
Molecular Weight 90.121
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Butylene glycol, or 1, 3-Butanediol, is an organic compoud found in peppers (Capsicum annuum). It is used as a solvent for flavoring agents, as a viscosity-descreasing agent in cosmetics and skin care products and as a hypoglycaemic agent for diabetics.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
REVERSE IT KIT

Approved Use

PROTECTS AGAINST SUNBURN

Launch Date

1.40400001E12
PubMed

PubMed

TitleDatePubMed
Purification and characterization of L-2,3-butanediol dehydrogenase of Brevibacterium saccharolyticum C-1012 expressed in Escherichia coli.
2001 Aug
Subtilisin-catalyzed synthesis of amino acid and peptide esters. Application in a two-step enzymatic ligation strategy.
2001 Dec 27
Adverse events, including death, associated with the use of 1,4-butanediol.
2001 Jan 11
Biodegradation of aliphatic-aromatic copolyesters: evaluation of the final biodegradability and ecotoxicological impact of degradation intermediates.
2001 Jul
Hydrolytic degradation of poly(carbonate)-urethanes by monocyte-derived macrophages.
2001 Nov
Redirection of pyruvate catabolism in Lactococcus lactis by selection of mutants with additional growth requirements.
2001 Sep
[GHB--dangerous, addictive and uncontrollable "party drug"].
2001 Sep 19
Utilization of quinolone drugs as monomers: characterization of the synthesis reaction products for poly(norfloxacin diisocyanatododecane polycaprolactone).
2001 Spring
Phase separation and physical properties of PEO-containing poly(ether ester amide)s.
2002
The effect of oxidation on the enzyme-catalyzed hydrolytic biodegradation of poly(urethane)s.
2002
Treatment of a 1,4-butanediol poisoning with fomepizole.
2002
Capillary gas chromatographic determination of 1,4-butanediol and gamma-hydroxybutyrate in human plasma and urine.
2002 Apr 5
Simultaneous analysis of gamma-hydroxybutyric acid, gamma-butyrolactone, and 1,4-butanediol by micellar electrokinetic chromatography.
2002 Feb 18
A novel route for synthesis of gamma-butyrolactone through the coupling of hydrogenation and dehydrogenation.
2002 Feb 7
Surface characterization and platelet adhesion studies of aliphatic polyurethanes grafted by fluorocarbon oligomers: effect of fluorocarbon chain length and carboxylic acid group.
2002 Jan
WBC filtration of whole blood after prolonged storage at ambient temperature by use of an in-line filter collection system.
2002 Jun
Anabolic androgenic steroid affects competitive behaviour, behavioural response to ethanol and brain serotonin levels.
2002 Jun 15
A simple GC method for determination of cryoprotector diols 1,4-butanediol or 2,3-butanediol in isolated rat hepatocytes.
2002 Mar-Apr
Human macrophage-mediated biodegradation of polyurethanes: assessment of candidate enzyme activities.
2002 Oct
Production of a polyester degrading extracellular hydrolase from Thermomonospora fusca.
2002 Sep-Oct
Purification and characterization of novel salt-active acharan sulfate lyase from Bacteroides stercoris HJ-15.
2003 Aug
Adenosine-5'-O-phosphorylated and adenosine-5'-O-phosphorothioylated polyols as strong inhibitors of (symmetrical) and (asymmetrical) dinucleoside tetraphosphatases.
2003 Jul 15
Lipase-catalyzed enantioselective esterification of (S)-naproxen hydroxyalkyl ester in organic media.
2003 Mar
Chiral direction and interconnection of helical three-connected networks in metal-organic frameworks.
2003 Mar 10
Lipase-catalyzed polycondensations: effect of substrates and solvent on chain formation, dispersity, and end-group structure.
2003 May-Jun
Cellular interactions and degradation of aliphatic poly(ester amide)s derived from glycine and/or 4-amino butyric acid.
2003 Sep
Production of L-2,3-butanediol by a new pathway constructed in Escherichia coli.
2004
The gamma-hydroxybutyrate withdrawal syndrome.
2004
Comparison of the actions of gamma-butyrolactone and 1,4-butanediol in Swiss-Webster mice.
2004 Apr
Changes in macrophage function and morphology due to biomedical polyurethane surfaces undergoing biodegradation.
2004 Apr
Butane-1,4-diyl bis(chloroacetate).
2004 Dec
Preparation of macrocyclic 15N-labelled oligoaminodeoxysaccharides as probes for RNA-binding.
2004 Dec 7
Determination of gamma-hydroxybutyric acid in biological fluids by using capillary electrophoresis with indirect detection.
2004 Feb 5
Development of a solid-phase extraction method for simultaneous extraction of adipic acid, succinic acid and 1,4-butanediol formed during hydrolysis of poly(butylene adipate) and poly(butylene succinate).
2004 Jan 2
Comparison of monolithic silica and polymethacrylate capillary columns for LC.
2004 Jul
Influence of reinforcer type and route of administration on gamma-hydroxybutyrate discrimination in rats.
2004 Jul
Monolithic columns with mixed modes of reversed-phase and anion-exchange stationary phase for capillary electrochromatography.
2004 Jul 30
4-methylpyrazole decreases 1,4-butanediol toxicity by blocking its in vivo biotransformation to gamma-hydroxybutyric acid.
2004 Oct
Enhanced production of acetoin and butanediol in recombinant Enterobacter aerogenes carrying Vitreoscilla hemoglobin gene.
2004 Oct
GHB (gamma-hydroxybutyrate) carrier-mediated transport across the blood-brain barrier.
2004 Oct
Optimization of binary porogen solvent composition for preparation of butyl methacrylate monoliths in capillary liquid chromatography.
2004 Sep 17
Biodegradation of aliphatic homopolyesters and aliphatic-aromatic copolyesters by anaerobic microorganisms.
2004 Sep-Oct
Physical characterizations of microemulsion systems using tocopheryl polyethylene glycol 1000 succinate (TPGS) as a surfactant for the oral delivery of protein drugs.
2005 Feb 2
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 16 15:48:32 UTC 2022
Edited
by admin
on Fri Dec 16 15:48:32 UTC 2022
Record UNII
3XUS85K0RA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BUTYLENE GLYCOL
II   INCI  
INCI  
Official Name English
1,3-BUTANEDIOL
HSDB  
Systematic Name English
1,3-BUTYLENE GLYCOL [MI]
Common Name English
NSC-402145
Code English
1,3 BUTYLENE GLYCOL [FHFI]
Common Name English
BUTYLENE GLYCOL [INCI]
Common Name English
1,3-BUTYLENE GLYCOL [FCC]
Common Name English
1,3-BUTANDIOL
WHO-DD  
Systematic Name English
1,3-DIHYDROXYBUTANE
Systematic Name English
1,3-Butylene glycol
FCC   MI  
Systematic Name English
1,3 BUTYLENE GLYCOL, (±)-
Common Name English
BUTANE-1,3-DIOL
USP-RS  
Systematic Name English
1,3-BUTANEDIOL [HSDB]
Common Name English
BUTYLENE GLYCOL [II]
Common Name English
(RS)-1,3-BUTANDIOL
Systematic Name English
1-METHYL-1,3-PROPANEDIOL
Systematic Name English
BUTANE-1,3-DIOL [USP-RS]
Common Name English
1,3-butandiol [WHO-DD]
Common Name English
1,3 BUTYLENE GLYCOL
FHFI  
Systematic Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 42205
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
CFR 21 CFR 172.712
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
CFR 21 CFR 173.220
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
Code System Code Type Description
DAILYMED
3XUS85K0RA
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
EVMPD
SUB22470
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
DRUG BANK
DB14110
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
RS_ITEM_NUM
1082956
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
EVMPD
SUB20839
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
EPA CompTox
DTXSID8026773
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
PUBCHEM
7896
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
CONCEPT Industrial Aid
WIKIPEDIA
1,3-BUTANEDIOL
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
EVMPD
SUB96179
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
MERCK INDEX
M2840
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY Merck Index
FDA UNII
3XUS85K0RA
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
ECHA (EC/EINECS)
203-529-7
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
RXCUI
1310542
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY RxNorm
NSC
402145
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
MESH
C028491
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
CAS
107-88-0
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
HSDB
153
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
CHEBI
52683
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
NCI_THESAURUS
C77457
Created by admin on Fri Dec 16 15:48:33 UTC 2022 , Edited by admin on Fri Dec 16 15:48:33 UTC 2022
PRIMARY
Related Record Type Details
ACTIVE MOIETY