U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:22:07 GMT 2023
Edited
by admin
on Sat Dec 16 14:22:07 GMT 2023
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
3XPI7EG4W8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Patritumab Deruxtecan
INN   USAN  
Official Name English
ANTI-HER3 ANTIBODY-DRUG CONJUGATE U3 1402
Common Name English
patritumab deruxtecan [INN]
Common Name English
U3-1402A
Code English
PATRITUMAB DERUXTECAN [JAN]
Common Name English
Immunoglobulin G1, anti-(human epidermal growth factor receptor HER3) (human monoclonal U3-1287 γ1-chain), complex with human monoclonal U3-1287 κ-chain, dimer, octakis(thioether) with N-[6-(3-mercapto-2,5-dioxo-1-pyrrolidinyl)-1-oxohexyl]glycylglycyl-
Common Name English
U31402
Code English
Patritumab deruxtecan [WHO-DD]
Common Name English
U3-1402
Code English
Immunoglobulin G1-kappa, anti-[Homo sapiens ERBB3 (receptor tyrosine-protein kinase erbB-3, HER3)], Homo sapiens monoclonal antibody, conjugated to deruxtecan, comprising a linker and a camptothecin derivative; gamma1 heavy chain Homo sapiens (1-447) [VH
Common Name English
PATRITUMAB DERUXTECAN [USAN]
Common Name English
Code System Code Type Description
INN
11093
Created by admin on Sat Dec 16 14:22:07 GMT 2023 , Edited by admin on Sat Dec 16 14:22:07 GMT 2023
PRIMARY
USAN
KL-231
Created by admin on Sat Dec 16 14:22:07 GMT 2023 , Edited by admin on Sat Dec 16 14:22:07 GMT 2023
PRIMARY
CAS
2227102-46-5
Created by admin on Sat Dec 16 14:22:07 GMT 2023 , Edited by admin on Sat Dec 16 14:22:07 GMT 2023
PRIMARY
FDA UNII
3XPI7EG4W8
Created by admin on Sat Dec 16 14:22:07 GMT 2023 , Edited by admin on Sat Dec 16 14:22:07 GMT 2023
PRIMARY
NCI_THESAURUS
C136987
Created by admin on Sat Dec 16 14:22:07 GMT 2023 , Edited by admin on Sat Dec 16 14:22:07 GMT 2023
PRIMARY
From To
1_22 1_95
1_144 1_200
1_261 1_321
1_367 1_425
2_22 2_95
2_144 2_200
2_261 2_321
2_367 2_425
3_23 3_94
3_140 3_200
4_23 4_94
4_140 4_200
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_52
N 1_297
N 2_52
N 2_297
Related Record Type Details
TARGET->LIGAND
PARENT -> DERIVATIVE
TARGET->CONJUGATED TOXIN
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL