Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H9N3 |
| Molecular Weight | 123.1558 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
N#CCCNCCC#N
InChI
InChIKey=SBAJRGRUGUQKAF-UHFFFAOYSA-N
InChI=1S/C6H9N3/c7-3-1-5-9-6-2-4-8/h9H,1-2,5-6H2
| Molecular Formula | C6H9N3 |
| Molecular Weight | 123.1558 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Acute toxic effects of 3,3'-iminodipropionitrile on hypothalamic-pituitary-gonadal axis in male rats. | 2014-01 |
|
| Role of CYP2E1-mediated metabolism in the acute and vestibular toxicities of nineteen nitriles in the mouse. | 2012-01-25 |
|
| Acute reproductive toxicity of 3,3'-iminodipropionitrile in female rats. | 2012-01 |
|
| Clinical physiology and mechanism of dizocilpine (MK-801): electron transfer, radicals, redox metabolites and bioactivity. | 2010-08-19 |
|
| Pentoxifylline attenuates iminodipropionitrile-induced behavioral abnormalities in rats. | 2009-07 |
|
| Nervous and vestibular toxicities of acrylonitrile and iminodipropionitrile. | 2009-07 |
|
| Neurovestibular toxicities of acrylonitrile and iminodipropionitrile in rats: a comparative evaluation of putative mechanisms and target sites. | 2009-05 |
|
| Phosphorylation and compactness of neurofilaments in multiple sclerosis: indicators of axonal pathology. | 2008-10 |
|
| [Curative effect and possible mechanisms of topiramate in treatment of Tourette syndrome in rats]. | 2008-08 |
|
| Requirement of vimentin filament assembly for beta3-adrenergic receptor activation of ERK MAP kinase and lipolysis. | 2007-03-23 |
|
| Protective effect of hydrocortisone on iminodipropionitrile-induced neurotoxicity in rats. | 2007-03 |
|
| Behavioral disturbances and hair cell loss in the inner ear following nitrile exposure in mice, guinea pigs, and frogs. | 2007-03 |
|
| Propagation of scrapie in peripheral nerves after footpad infection in normal and neurotoxin exposed hamsters. | 2006-05-29 |
|
| Mechanism of neurotoxic 3,3'-iminodipropionitrile: relation to unsaturated nitriles, cocaine, and reactive oxygen species. | 2006 |
|
| Behavioral and pathological effects in the rat define two groups of neurotoxic nitriles. | 2005-12 |
|
| Does copper ameliorate the vestibular toxicity of iminodipropionitrile (IDPN)? | 2005-06 |
|
| Extruding auditory hair cells in rats exposed to subchronic 3,3'-iminodipropionitrile. | 2005-05 |
|
| The neurotoxicity of iminodipropionitrile (IDPN) is ameliorated by copper. | 2005-03 |
|
| On the similarity of cocaine and 3,3'-iminodipropionitrile. | 2005 |
|
| Role of oxidative metabolites of cocaine in toxicity and addiction: oxidative stress and electron transfer. | 2005 |
|
| Sodium benzoate attenuates iminodipropionitrile-induced behavioral syndrome in rats. | 2004-12 |
|
| Metoclopramide attenuates iminodipropionitrile-induced oxidative stress and neurobehavioral toxicity in rats. | 2004-11 |
|
| Retinal microvascular patency in the diabetic rat. | 2004-07 |
|
| Inhibitory effect of free radical scavenger, MCI-186, in the increase of hydroxyl radical induced by iminodipropionitrile in rats. | 2004-04-15 |
|
| Distal effects in a model of proximal axonopathy: 3,3'-iminodipropionitrile causes specific loss of neurofilaments in rat vestibular afferent endings. | 2003-11 |
|
| Influence of age on iminodipropionitrile-induced vestibular and neurobehavioral toxicities in rats. | 2003-09 |
|
| Expression of neurotransmitter genes in motor regions of the dyskinetic rat after iminodipropionitrile. | 2003-08-14 |
|
| A hypothetical mathematical construct explaining the mechanism of biological amplification in an experimental model utilizing picoTesla (PT) electromagnetic fields. | 2003-06 |
|
| Three-dimensional mapping of the lesions induced by beta-beta'-iminodiproprionitrile, methyl iodide and methyl methacrylate in the rat nasal cavity. | 2003-05-15 |
|
| [Neurobehavioral toxicity of acrylamide and IDPN (3,3'-iminodipropionitrile) in rats by 28-day oral administration--problems encountered in collaborative study and a commentary on conducting neurobehavioral testing]. | 2003-05 |
|
| Comparison of cis- and trans-crotononitrile effects in the rat reveals specificity in the neurotoxic properties of nitrile isomers. | 2003-03-01 |
|
| Attenuation of iminodipropionitrile induced behavioral syndrome by sodium salicylate in rats. | 2002-10 |
|
| Masses of phosphorylated neurofilaments are associated with abnormal golgi apparatus of anterior horn neurons of beta, beta'-iminodipropionitrile-intoxicated rats. | 2002-06 |
|
| Relationship between insult intensity and mode of hair cell loss in the vestibular system of rats exposed to 3,3'-iminodipropionitrile. | 2001-10-29 |
|
| Pathology of the rat vestibular sensory epithelia during subchronic 3,3'-iminodipropionitrile exposure: hair cells may not be the primary target of toxicity. | 2001-10 |
|
| Behavioural disturbances and sensory pathology following allylnitrile exposure in rats. | 2001-06-22 |
|
| Characterization of olfactory deficits in the rat following administration of 2,6-dichlorobenzonitrile (dichlobenil), 3,3'-iminodipropionitrile, or methimazole. | 1996-01 |
|
| The ototoxicity of 3,3'-iminodipropionitrile: functional and morphological evidence of cochlear damage. | 1994-11 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:02:59 GMT 2025
by
admin
on
Mon Mar 31 19:02:59 GMT 2025
|
| Record UNII |
3XP1CVU865
|
| Record Status |
Validated (UNII)
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| Record Version |
|
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Download
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Systematic Name | English | ||
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Preferred Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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EPA PESTICIDE CODE |
600004
Created by
admin on Mon Mar 31 19:02:59 GMT 2025 , Edited by admin on Mon Mar 31 19:02:59 GMT 2025
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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111-94-4
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PRIMARY | |||
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203-922-3
Created by
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PRIMARY | |||
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3XP1CVU865
Created by
admin on Mon Mar 31 19:02:59 GMT 2025 , Edited by admin on Mon Mar 31 19:02:59 GMT 2025
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8149
Created by
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7770
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5539
Created by
admin on Mon Mar 31 19:02:59 GMT 2025 , Edited by admin on Mon Mar 31 19:02:59 GMT 2025
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IDPN (chemical)
Created by
admin on Mon Mar 31 19:02:59 GMT 2025 , Edited by admin on Mon Mar 31 19:02:59 GMT 2025
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DTXSID2041464
Created by
admin on Mon Mar 31 19:02:59 GMT 2025 , Edited by admin on Mon Mar 31 19:02:59 GMT 2025
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PRIMARY |