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Details

Stereochemistry ACHIRAL
Molecular Formula C2H5O4S.Na
Molecular Weight 148.113
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM ISETHIONATE

SMILES

[Na+].OCCS([O-])(=O)=O

InChI

InChIKey=LADXKQRVAFSPTR-UHFFFAOYSA-M
InChI=1S/C2H6O4S.Na/c3-1-2-7(4,5)6;/h3H,1-2H2,(H,4,5,6);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula C2H5O4S
Molecular Weight 125.124
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis.
2010-11-15
Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis.
2010-10-05
Effects of taurine on male reproduction in rats of different ages.
2010-08-24
Effect of beta-alanine treatment on mitochondrial taurine level and 5-taurinomethyluridine content.
2010-08-24
Highly efficient procedure for the synthesis of fructone fragrance using a novel carbon based acid.
2010-08-05
Diverse effects on mitochondrial and nuclear functions elicited by drugs and genetic knockdowns in bloodstream stage Trypanosoma brucei.
2010-05-04
Antileishmanial high-throughput drug screening reveals drug candidates with new scaffolds.
2010-05-04
Drug resistance in leishmaniasis.
2010-05
Treatment strategies for mucocutaneous leishmaniasis.
2010-05
Isethionate formation from taurine in Chromohalobacter salexigens: purification of sulfoacetaldehyde reductase.
2010-05
Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation.
2010-02-09
Incorporation of ionic ligands accelerates drug release from LDI-glycerol polyurethanes.
2010-01
Identification of potent chemotypes targeting Leishmania major using a high-throughput, low-stringency, computationally enhanced, small molecule screen.
2009-11-03
East African trypanosomiasis in a pregnant traveler.
2009-11
Leishmania killicki imported from Tunisian desert.
2009-11
Rapid modification of proteins using a rapamycin-inducible tobacco etch virus protease system.
2009-10-15
Drugs associated with more suicidal ideations are also associated with more suicide attempts.
2009-10-02
Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal.
2009-09-29
Cutaneous and mucocutaneous leishmaniasis in Tigray, northern Ethiopia: clinical aspects and therapeutic concerns.
2009-07
Interventions for American cutaneous and mucocutaneous leishmaniasis.
2009-04-15
Effect of free versus liposomal-complexed pentamidine isethionate on biological characteristics of Acanthamoeba castellanii in vitro.
2009-03
In leishmaniasis due to Leishmania guyanensis infection, distinct intralesional interleukin-10 and Foxp3 mRNA expression are associated with unresponsiveness to treatment.
2009-02-15
A controlled, randomized nonblinded clinical trial to assess the efficacy of amphotericin B deoxycholate as compared to pentamidine for the treatment of antimony unresponsive visceral leishmaniasis cases in Bihar, India.
2009-02
Evaluation of treatment with pentamidine for cutaneous leishmaniasis in Suriname.
2009-01
Electrochemical synthesis of polyaniline nano-networks on p-aminobenzene sulfonic acid functionalized glassy carbon electrode Its use for the simultaneous determination of ascorbic acid and uric acid.
2008-12-01
The blood-brain barrier significantly limits eflornithine entry into Trypanosoma brucei brucei infected mouse brain.
2008-11
Blood collection from the American horseshoe crab, Limulus polyphemus.
2008-10-13
Diffuse skin spread of HIV-associated visceral leishmaniasis: cumbersome diagnostic and therapeutic issues.
2008-10
Anionic selectivity sequence of the Cl(-)-H+ symporter in the synaptosomal preparation from rat brain cortex.
2008-08
Effect of mesoionic 4-phenyl-5-(cinnamoyl)-1,3,4-thiadiazolium-2-phenylamine chloride derivative salts on the activities of the nitric oxide synthase and arginase of Leishmania amazonensis.
2008-06
Using the zebrafish lateral line to screen for ototoxicity.
2008-06
Pentamidine dosage: a base/salt confusion.
2008-05-28
Transporter-mediated GABA responses in horizontal and bipolar cells of zebrafish retina.
2008-04-30
Comparative efficacy assessment of pentamidine isethionate and diminazene aceturate in the chemotherapy of Trypanosoma brucei brucei infection in dogs.
2008-02-14
Characterizing the effect of pentamidine isethionate on the immune system using mouse splenocytes as an experimental model.
2007-10
Recurrent American cutaneous leishmaniasis.
2007-09
The DUF81 protein TauE in Cupriavidus necator H16, a sulfite exporter in the metabolism of C2 sulfonates.
2007-09
Cellulose biosynthesis pathway is a potential target in the improved treatment of Acanthamoeba keratitis.
2007-05
Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores.
2007-03-06
Depolarization evoked by acetylcholine in mesenteric arteries of hypertensive rats attenuates endothelium-dependent hyperpolarizing factor.
2007-02
Cl- channels of the distal nephron.
2006-12
[Efficacy and tolerance of pentamidine for treatment of cutaneous leishmaniasis caused by por L. (V) panamensis in Colombia].
2006-10
Effect of polyvinylpyrrolidone and sodium lauroyl isethionate on kaolinite suspension in an aqueous phase.
2006-08
Development of a semi-automated colorimetric assay for screening anti-leishmanial agents.
2006-07
Efficacy of short-course intramuscular pentamidine isethionate treatment on Old World localized cutaneous leishmaniasis in 2 patients.
2006-06-15
Comparison between one and two injections of pentamidine isethionate, at 7 mg/kg in each injection, in the treatment of cutaneous leishmaniasis in French Guiana.
2006-06
Changes in composition of spider orb web sticky droplets with starvation and web removal, and synthesis of sticky droplet compounds.
2006-04
A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats.
2006-01
Pentamidine is an antiparasitic and apoptotic drug that selectively modifies ubiquitin.
2005-10
Amidine derivatives and Leishmania amazonensis: an evaluation of the effect of nitric oxide (NO) production on the parasite-macrophage interaction.
2005-02
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:29:45 GMT 2025
Edited
by admin
on Mon Mar 31 19:29:45 GMT 2025
Record UNII
3R36J71C17
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM ISETHIONATE
HSDB   INCI  
INCI  
Official Name English
NSC-124283
Preferred Name English
SODIUM ISETHIONATE [HSDB]
Common Name English
SODIUM 2-HYDROXYETHANESULFONIC ACID
Systematic Name English
ISETHIONATE, SODIUM SALT
Common Name English
ETHANESULFONIC ACID, 2-HYDROXY-, MONOSODIUM SALT
Common Name English
2-HYDROXYETHANESULFONIC ACID, SODIUM SALT
Common Name English
Code System Code Type Description
NSC
124283
Created by admin on Mon Mar 31 19:29:45 GMT 2025 , Edited by admin on Mon Mar 31 19:29:45 GMT 2025
PRIMARY
CAS
1562-00-1
Created by admin on Mon Mar 31 19:29:45 GMT 2025 , Edited by admin on Mon Mar 31 19:29:45 GMT 2025
PRIMARY
FDA UNII
3R36J71C17
Created by admin on Mon Mar 31 19:29:45 GMT 2025 , Edited by admin on Mon Mar 31 19:29:45 GMT 2025
PRIMARY
DAILYMED
3R36J71C17
Created by admin on Mon Mar 31 19:29:45 GMT 2025 , Edited by admin on Mon Mar 31 19:29:45 GMT 2025
PRIMARY
HSDB
5838
Created by admin on Mon Mar 31 19:29:45 GMT 2025 , Edited by admin on Mon Mar 31 19:29:45 GMT 2025
PRIMARY
PUBCHEM
517063
Created by admin on Mon Mar 31 19:29:45 GMT 2025 , Edited by admin on Mon Mar 31 19:29:45 GMT 2025
PRIMARY
EPA CompTox
DTXSID7027413
Created by admin on Mon Mar 31 19:29:45 GMT 2025 , Edited by admin on Mon Mar 31 19:29:45 GMT 2025
PRIMARY
ECHA (EC/EINECS)
216-343-6
Created by admin on Mon Mar 31 19:29:45 GMT 2025 , Edited by admin on Mon Mar 31 19:29:45 GMT 2025
PRIMARY
RXCUI
1364895
Created by admin on Mon Mar 31 19:29:45 GMT 2025 , Edited by admin on Mon Mar 31 19:29:45 GMT 2025
PRIMARY RxNorm
WIKIPEDIA
Sodium 2-hydroxyethyl sulfonate
Created by admin on Mon Mar 31 19:29:45 GMT 2025 , Edited by admin on Mon Mar 31 19:29:45 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE