Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | 2C7H7O5S.2K.H2O |
| Molecular Weight | 502.597 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.[K+].[K+].COC1=CC(=CC=C1O)S([O-])(=O)=O.COC2=CC(=CC=C2O)S([O-])(=O)=O
InChI
InChIKey=AHTXUEDLGSAAMV-UHFFFAOYSA-L
InChI=1S/2C7H8O5S.2K.H2O/c2*1-12-7-4-5(13(9,10)11)2-3-6(7)8;;;/h2*2-4,8H,1H3,(H,9,10,11);;;1H2/q;;2*+1;/p-2
| Molecular Formula | K |
| Molecular Weight | 39.0983 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C7H7O5S |
| Molecular Weight | 203.192 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | H2O |
| Molecular Weight | 18.0153 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Potassium 4-Hydroxy-3-methoxybenzenesulfonate Hemihydrate is the hemihydrate of potassium guaiacolsulfonate. Guaiacolsulfonic acid, commonly used in the form of potassium guaiacolsulfonate. Guaiacolsulfonic acid is used as an expectorant for relieving symptoms of cough and mucus in the chest due to respiratory infections, asthma, colds, or hay fever. Guaiacolsulfonate works by thinning mucus (phlegm) in the lungs and making it less sticky and easier to cough up. 'is reduces chest congestion by making coughs more productive.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Development and Validation of an HPLC Method for Simultaneous Assay of Potassium Guaiacolsulfonate and Sodium Benzoate in Pediatric Oral Powder. | 2019 |
|
| A New UPLC Approach for the Simultaneous Quantitative Estimation of Four Compounds in a Cough Syrup Formulation. | 2016-01 |
|
| Simultaneous determination of potassium guaiacolsulfonate, guaifenesin, diphenhydramine HCl and carbetapentane citrate in syrups by using HPLC-DAD coupled with partial least squares multivariate calibration. | 2011-02-15 |
|
| Physicochemical properties and method for determination of potassium guaiacolsulfonate. | 1987-07-01 |
|
| Determination of the chemical constituents and spectral properties of commercial and NF reference standard potassium guaiacolsulfonate: implications of the findings on compendial analytical methodology. | 1984-09 |
|
| Spectrophotometric determination of bromhexine hydrochloride in pharmaceutical preparations. | 1984-05-01 |
|
| Applications of paired ion high-pressure liquid chromatography: quantitative determination of potassium guaiacolsulfonate and other ingredients in cough syrups. | 1979-01 |
|
| Quantitative determination of four antihistamines in combination by high-pressure liquid chromatography. | 1977-06 |
|
| Determination of potassium guaiacolsulfonate by ion-pairing partition chromatography. | 1975-03 |
|
| [Determination of sodium camphosulfonate in the presence of potassium guaiacolsulfonate]. | 1963-01 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:22:45 GMT 2025
by
admin
on
Mon Mar 31 18:22:45 GMT 2025
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| Record UNII |
3QSR9RW0V3
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| Record Status |
Validated (UNII)
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| Record Version |
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73416547
Created by
admin on Mon Mar 31 18:22:45 GMT 2025 , Edited by admin on Mon Mar 31 18:22:45 GMT 2025
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3QSR9RW0V3
Created by
admin on Mon Mar 31 18:22:45 GMT 2025 , Edited by admin on Mon Mar 31 18:22:45 GMT 2025
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ANHYDROUS->SOLVATE | |||
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PARENT -> SALT/SOLVATE |
