PROPAZONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H15NO3
Molecular Weight	185.2203
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCC1(CCC)OC(=O)NC1=O

InChI

InChIKey=BVTOXVHDKWVNBF-UHFFFAOYSA-N

InChI=1S/C9H15NO3/c1-3-5-9(6-4-2)7(11)10-8(12)13-9/h3-6H2,1-2H3,(H,10,11,12)

HIDE SMILES / InChI

Molecular Formula	C9H15NO3
Molecular Weight	185.2203
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
In Utero Exposure to a Cardiac Teratogen Causes Reversible Deficits in Postnatal Cardiovascular Function, But Altered Adaptation to the Burden of Pregnancy.	2015-11	26311034
Maternal rat serum concentrations of dimethadione do not explain intra-litter differences in the incidence of dimethadione-induced birth defects, including novel findings in foetal lung.	2014-12-04	25446330
In utero dimethadione exposure causes postnatal disruption in cardiac structure and function in the rat.	2014-12	25239635
Alterations in mouse embryo intracellular pH by DMO during culture impair implantation and fetal growth.	2010-08	20615756
Acidic and basic solutions dissolve protein plugs made of lithostathine complicating choledochal cyst/pancreaticobiliary maljunction.	2009-07	18989781
Review of levetiracetam, with a focus on the extended release formulation, as adjuvant therapy in controlling partial-onset seizures.	2009	19777068
Glucose loading precipitates focal lactic acidosis in the vulnerable medial thalamus of thiamine-deficient rats.	2008-03	18034292
Polytherapy with hERG-blocking antiepileptic drugs: increased risk for embryonic cardiac arrhythmia and teratogenicity.	2007-08	17584909
Embryonic cardiac arrhythmia and generation of reactive oxygen species: common teratogenic mechanism for IKr blocking drugs.	2007-07	17570632
Pharmacological evidence that stalk cell differentiation involves increases in the intracellular Ca(2+) and H(+) concentrations in Dictyostelium discoideum.	2007-04	17394603
Thoracic skeletal defects and cardiac malformations: a common epigenetic link?	2006-12	17315248
Interactive effects of cadmium and all-trans-retinoic acid on the induction of forelimb ectrodactyly in C57BL/6 mice.	2006-01	16369952
Discriminative power of an assay for automated in vitro screening of teratogens.	2004-08	15130609
Disruption of bovine oocytes and preimplantation embryos by urea and acidic pH.	2003-04	12741544
Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs?	2002-05	12027905
Selection of test chemicals for the ECVAM international validation study on in vitro embryotoxicity tests. European Centre for the Validation of Alternative Methods.	2002-04-25	11971754
The clinical importance of the trimethadione tolerance test as a method for quantitative assessment of hepatic functional reserve in patients with biliary atresia.	2001-12	11722678
Na(+)-dependent pH regulation by the amitochondriate protozoan parasite Giardia intestinalis.	2001-08-03	11297564
Altering intracellular pH disrupts development and cellular organization in preimplantation hamster embryos.	2001-06	11369617
Trimethadione N-demethylation by rat liver CYP2E1 in vitro.	1996-07	8865369

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:53:06 GMT 2025` Edited by `admin` on `Mon Mar 31 22:53:06 GMT 2025`
Record UNII	3Q181RIU8E
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

5,5-DIPROPYL-2,4-OXAZOLIDINEDIONE

Preferred Name

English

PROPAZONE

Common Name

English

2,4-OXAZOLIDINEDIONE, 5,5-DIPROPYL-

Systematic Name

English

5,5-DIPROPYL-2,4-OXAZOLIDINEDIONE [MI]

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID20275778