U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:51:02 GMT 2023
Edited
by admin
on Sat Dec 16 14:51:02 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
3PT70X17VS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BAVUNALIMAB
USAN   INN  
Official Name English
IMMUNOGLOBULIN, ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4) (HUMAN-MUS MUSCULUS MONOCLONAL XMAB22841 SINGLE-CHAIN VARIABLE FRAGMENT VH-LINKER-VL) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN .GAMMA.1-CHAIN C-REGION C-TERMINAL FRAGMENT), (257
Common Name English
ANTI-CTLA-4/LAG-3 BISPECIFIC ANTIBODY XMAB22841
Common Name English
XMAB-22841
Code English
XMAB22841
Code English
bavunalimab [INN]
Common Name English
PAVUNALIMAB
Common Name English
BAVUNALIMAB [USAN]
Common Name English
IMMUNOGLOBULIN HALF-IG G1-KAPPA/SCFV-H-CH2-CH3, ANTI-(HOMO SAPIENS LAG3 (LYMPHOCYTE ACTIVATING 3, LYMPHOCYTE-ACTIVATION 3, CD223)) AND ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), MONOCLONAL ANTIBODY, BISPECIFIC; GAMMA1
Common Name English
Code System Code Type Description
INN
11465
Created by admin on Sat Dec 16 14:51:02 GMT 2023 , Edited by admin on Sat Dec 16 14:51:02 GMT 2023
PRIMARY
NCI_THESAURUS
C159530
Created by admin on Sat Dec 16 14:51:02 GMT 2023 , Edited by admin on Sat Dec 16 14:51:02 GMT 2023
PRIMARY
CAS
2250088-66-3
Created by admin on Sat Dec 16 14:51:02 GMT 2023 , Edited by admin on Sat Dec 16 14:51:02 GMT 2023
NO STRUCTURE GIVEN
USAN
JK-27
Created by admin on Sat Dec 16 14:51:02 GMT 2023 , Edited by admin on Sat Dec 16 14:51:02 GMT 2023
PRIMARY
FDA UNII
3PT70X17VS
Created by admin on Sat Dec 16 14:51:02 GMT 2023 , Edited by admin on Sat Dec 16 14:51:02 GMT 2023
PRIMARY
CAS
2329669-78-3
Created by admin on Sat Dec 16 14:51:02 GMT 2023 , Edited by admin on Sat Dec 16 14:51:02 GMT 2023
PRIMARY
From To
1_260 2_233
1_257 2_230
2_224 3_218
3_138 3_198
3_23 3_92
2_370 2_428
2_264 2_324
2_148 2_204
2_22 2_98
1_397 1_455
1_291 1_351
1_161 1_227
1_22 1_96
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_300
N 2_327
Related Record Type Details
TARGET -> INHIBITOR
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL