Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C4H10N3O4P.2Na |
| Molecular Weight | 241.0932 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[Na+].CN(CCOP([O-])([O-])=O)C(N)=N
InChI
InChIKey=SJDIYXXTYDHARQ-UHFFFAOYSA-L
InChI=1S/C4H12N3O4P.2Na/c1-7(4(5)6)2-3-11-12(8,9)10;;/h2-3H2,1H3,(H3,5,6)(H2,8,9,10);;/q;2*+1/p-2
| Molecular Formula | C4H10N3O4P |
| Molecular Weight | 195.1137 |
| Charge | -2 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Creatinolfosfate (or creatinol-O-phosphate, or COP) possesses anti-ischemic and anti-arrhythmic activities associated with improved ionic balance and heart performance. This compound exerts its cardioprotective effect by action on anaerobic glycolysis. The results of the toxicological studies showed that creatinolfosfate didn’t have side effects.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Treatment of antihiasthenic syndromes (with creatinol-O-phosphate)]. | 1976 Sep 30 |
|
| Protective effect of creatinol O-phosphate (COP) on ventricular fibrillation and death induced by intravenous CaCl2 in mice. | 1979 |
|
| An analysis of the reduction by creatinol O-phosphate of the myocardial lesions evoked by isoprenaline in the rat. | 1979 |
|
| Creatinol O-phosphate therapy in patients with inadequate coronary circulation. Double-blind clinical trial. | 1979 |
|
| Effects of creatinol O-phosphate on serum enzymes in acute myocardial infarction. | 1979 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:59:24 GMT 2023
by
admin
on
Sat Dec 16 09:59:24 GMT 2023
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| Record UNII |
3PL85389NX
|
| Record Status |
Validated (UNII)
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| Record Version |
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6903-80-6
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3PL85389NX
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45382237
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