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Details

Stereochemistry ACHIRAL
Molecular Formula C6H14O4
Molecular Weight 150.173
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRIETHYLENE GLYCOL

SMILES

OCCOCCOCCO

InChI

InChIKey=ZIBGPFATKBEMQZ-UHFFFAOYSA-N
InChI=1S/C6H14O4/c7-1-3-9-5-6-10-4-2-8/h7-8H,1-6H2

HIDE SMILES / InChI
Molecular Formula C6H14O4
Molecular Weight 150.173
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including: https://www.drugs.com/dict/triethylene-glycol.html | https://www.ncbi.nlm.nih.gov/pubmed/28207892

Triethylene glycol is used in the vapor state as an air-sterilizing agent, toxic to bacteria, fungi and viruses in low concentrations in air. It is used in cosmetics as a fragrance ingredient and as a viscosity-decreasing agent. Commercially available triethylene glycol increased non-rapid eye movement sleep in mice in a dose-dependent manner. These results clearly demonstrated that triethylene glycol could potentially be useful for insomnia therapy. Triethylene glycol is used for occasional constipation and other conditions.

Approval Year

1988
111
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Preclinical
Unknown

Approved Use

Unknown
Primary
Not Provided
504
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Self-assembly of a pi-electronic amphiphile consisting of a zinc porphyrin-fullerene dyad: formation of micro-vesicles with a high stability.
2004 Dec 7
Design of attachment type of drug delivery system by complex formation of avidin with biotinyl drug model and biotinyl saccharide.
2004 Feb 10
Oriented binding of the His6-tagged carboxyl-tail of the L-type Ca2+ channel alpha1-subunit to a new NTA-functionalized self-assembled monolayer.
2004 Jul 6
Removal of viruscide agents by using styrenic resins.
2004 May-Aug
Net expansion of dried demineralized dentin matrix produced by monomer/alcohol saturation and solvent evaporation.
2006 Nov
Chairside fabricated fiber-reinforced composite fixed partial denture.
2007 Mar 1
Fiber-reinforced Composite for Chairside Replacement of Anterior Teeth: A Case Report.
2008 Dec 1
Broadband dielectric study on the water-concentration dependence of the primary and secondary processes for triethyleneglycol-water mixtures.
2008 Jul
Wormlike micelles in mixed amino acid surfactant/nonionic surfactant aqueous systems and the effect of added electrolytes.
2009
Excretion of dental resin monomers and metabolic intermediates via urine in guinea pigs.
2009 Apr
Adherence of Streptococcus mutans to Fiber-Reinforced Filling Composite and Conventional Restorative Materials.
2009 Dec 4
Modulated morphology in the self-organization of a rectangular amphiphile.
2009 Jul 6
Synthesis of hydrophilic conjugated porphyrin dimers for one-photon and two-photon photodynamic therapy at NIR wavelengths.
2009 Mar 7
Development and application of a simplified sample preparation method for determination of TEGDMA and related metabolites.
2009 Oct
Molecular toxicology of substances released from resin-based dental restorative materials.
2009 Sep 4
Kinetic Studies and Mechanism of Hydrogen Peroxide Catalytic Decomposition by Cu(II) Complexes with Polyelectrolytes Derived from L-Alanine and Glycylglycine.
2010
Ultimate diastereoselectivity in the ring closure of photochromic diarylethene possessing facial chirality.
2010 Jul 14
Highly fluorinated cyclodextrins and their host-guest interactions.
2010 Jun 28
Encapsulation and stabilization of gold nanoparticles with "click" polyethyleneglycol dendrimers.
2010 Mar 3
Dendronized triangular oligo(phenylene ethynylene) amphiphiles: nanofibrillar self-assembly and dye encapsulation.
2010 Mar 8
Patents

Patents

JP1052691A
1
JP2000008089A
1
JP2000072767A
1
JP2001002828A
1
JP2001026489A
1
JP2001527505A
1
JP2002003842A
1
JP2002293758A
1
JP2002327141A
1
JP2003113335A
1
JP2003508498A
1
JP2004323544A
1
JP2004526678A
3
JP2004528401A
5
JP2004531594A
7
JP2005105120A
1
JP2005105121A
1
JP2005343996A
1
JP2005504662A
2
JP2006016346A
1
JP2006518209A
1
JP2007508312A
4
JP2007511641A
6
JP2007517946A
6
JP2008297507A
1
JP2008518861A
1
JP2010077495A
1
JP2010528150A
1
JP2011168690A
1
JP2011177401A
2
JP2011522411A
1
JP2011526890A
2
JP2012001551A
3
JP3395970B2
3
JP5377948B2
1
JPH00971658A
1
JPH01245421A
1
JPH01263148A
1
JPH01301637A
1
JPH01311163A
1
JPH0259568A
1
JPH04227690A
1
JPH04283240A
8
JPH0592902A
1
JPH06234956A
1
JPH0831610A
1
JPH09507875A
1
JPH10104554A
2
JPH10194917A
1
JPH10306174A
1
JPH11172171A
1

Sample Use Guides

In Vivo Use Guide
10–30 mg/mouse
Route of Administration: Oral
In Vitro Use Guide
Significant killing effects of Triethylene glycol vapor in low concentrations (1:100,000,000 or lower) at relative humidities between 42 and 62 per cent, but not at 15 per cent or at 79 per cent were reported at dynamic cloud of Salmonella pullorum.
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:12:22 UTC 2023
Edited
by admin
on Fri Dec 15 15:12:22 UTC 2023
Record UNII
3P5SU53360
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRIETHYLENE GLYCOL
HSDB   INCI   MI   USP-RS   WHO-DD  
INCI  
Official Name English
Triethylene glycol [WHO-DD]
Common Name English
POLYETHYLENE GLYCOL (3)
Common Name English
2,2'-(1,2-ETHANEDIYLBIS(OXY))BISETHANOL
Systematic Name English
MACROGOL 150
Common Name English
2,2'-ETHYLENEDIOXYBIS(ETHANOL)
Systematic Name English
TRIETHYLENE GLYCOL [HSDB]
Common Name English
PEG-3
Common Name English
TRIETHYLENE GLYCOL [USP-RS]
Common Name English
TRIETHYLENE GLYCOL [MI]
Common Name English
NSC-60758
Code English
POLYETHYLENE GLYCOL 150
Common Name English
TRIETHYLENE GLYCOL [INCI]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 83501
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
Code System Code Type Description
EPA CompTox
DTXSID4021393
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
CHEBI
44926
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
MERCK INDEX
m11105
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY Merck Index
NSC
60758
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
PUBCHEM
8172
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
DAILYMED
3P5SU53360
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
NCI_THESAURUS
C84227
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
CONCEPT Industrial Aid
CAS
112-27-6
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
ECHA (EC/EINECS)
203-953-2
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
EVMPD
SUB15612MIG
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
RS_ITEM_NUM
1683708
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
DRUG BANK
DB02327
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
SMS_ID
100000077276
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
MESH
C028914
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
RXCUI
1368702
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY RxNorm
FDA UNII
3P5SU53360
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
HSDB
898
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
WIKIPEDIA
TRIETHYLENE GLYCOL
Created by admin on Fri Dec 15 15:12:22 UTC 2023 , Edited by admin on Fri Dec 15 15:12:22 UTC 2023
PRIMARY
NIH
NCATS
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