BISPHENOL S

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H10O4S
Molecular Weight	250.27
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(O)C=C2

InChI

InChIKey=VPWNQTHUCYMVMZ-UHFFFAOYSA-N

InChI=1S/C12H10O4S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8,13-14H

HIDE SMILES / InChI

Molecular Formula	C12H10O4S
Molecular Weight	250.27
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Genome-wide gene expression profiling of low-dose, long-term exposure of human osteosarcoma cells to bisphenol A and its analogs bisphenols AF and S.	2015-08	25912373
Rapid responses and mechanism of action for low-dose bisphenol S on ex vivo rat hearts and isolated myocytes: evidence of female-specific proarrhythmic effects.	2015-06	25723814
Structural bisphenol analogues differentially target steroidogenesis in murine MA-10 Leydig cells as well as the glucocorticoid receptor.	2015-03-02	25576683
Comparing the effects of tetrabromobisphenol-A, bisphenol A, and their potential replacement alternatives, TBBPA-bis(2,3-dibromopropyl ether) and bisphenol S, on cell viability and messenger ribonucleic acid expression in chicken embryonic hepatocytes.	2015-02	25470364
Is bisphenol S a safe substitute for bisphenol A in terms of metabolic function? An in vitro study.	2014-10-15	25111128
Comparative study of bisphenol A and its analogue bisphenol S on human hepatic cells: a focus on their potential involvement in nonalcoholic fatty liver disease.	2014-08	24793377
Are structural analogues to bisphenol a safe alternatives?	2014-05	24563381
Exploring the interaction of bisphenol-S with serum albumins: a better or worse alternative for bisphenol a?	2014-04-10	24635450
In vitro study on the agonistic and antagonistic activities of bisphenol-S and other bisphenol-A congeners and derivatives via nuclear receptors.	2013-10-01	23714657
Bisphenol A affects androgen receptor function via multiple mechanisms.	2013-05-25	23562765
Bisphenol S disrupts estradiol-induced nongenomic signaling in a rat pituitary cell line: effects on cell functions.	2013-03	23458715
Weak estrogenic transcriptional activities of Bisphenol A and Bisphenol S.	2012-08	22507746
Determination of polymer electrolyte membrane (PEM) degradation products in fuel cell water using electrospray ionization tandem mass spectrometry.	2010-12-30	21080505
Rational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands.	2010-12-05	20869355
Sulfonated poly(arylene ether sulfone)s with phosphine oxide moieties: a promising material for proton exchange membranes.	2010-06	20507071
Micro-biofuel cell powered by glucose/O2 based on electro-deposition of enzyme, conducting polymer and redox mediators: preparation, characterization and performance in human serum.	2010-02-15	20005695
Biodegradation of bisphenol A, bisphenol F and bisphenol S in seawater.	2009-04	19440529
2-(4-Hydroxy-phenyl-sulfon-yl)phenol.	2009-01-28	21581986
Removal characteristics of endocrine-disrupting chemicals by laccase from white-rot fungi.	2008-01	18161558
Biodegradation of bisphenol A and related compounds by Sphingomonas sp. strain BP-7 isolated from seawater.	2007-01	17213659
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006-11	16497524
Biodegradation of a variety of bisphenols under aerobic and anaerobic conditions.	2006	16749452
Comparative study of the uterotrophic potency of 14 chemicals in a uterotrophic assay and their receptor-binding affinity.	2004-01-15	14643963
Peroxidase-catalyzed co-oxidation of 3,3',5,5'-tetramethylbenzidine in the presence of substituted phenols and their polydisulfides.	2004-01	14659626
Unexpected differences in the alpha-halogenation and related reactivity of sulfones with perhaloalkanes in KOH-t-BuOH.	2003-01-24	12530877
Peroxidase-catalyzed co-oxidation of 3,3',5,5'-tetramethylbenzidine with 2-amino-4-nitrophenol, 4,4'-dihydroxydiphenylsulfone, and their polydisulfides in aqueous and micellar media.	2001-06	11421808

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:34:10 GMT 2025` Edited by `admin` on `Mon Mar 31 18:34:10 GMT 2025`
Record UNII	3OX4RR782R
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NSC-683541

Preferred Name

English

BISPHENOL S

Common Name

English

4,4-SULFONYLDIPHENOL

Common Name

English

PHENOL, 4,4'-SULFONYLBIS-

Systematic Name

English

4,4'-SULFONYLDIPHENOL

Systematic Name

English

1, 1'-SULFONYLBIS(4-HYDROXYBENZENE)

Systematic Name

English

BISPHENOL-S

Common Name

English

BIS(4-HYDROXY(PHENYL))SULFONE

Systematic Name

English

1,1'-SULFONYLBIS(4-HYDROXYBENZENE)

Systematic Name

English

NSC-8712

Code

English

BIS(4-HYDROXY(PHENYL))SULPHONE

Systematic Name

English

SULPHONYLBISPHENOL

Systematic Name

English

Code System Code Type Description

CAS

80-09-1