ULILEDLIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 23:43:08 GMT 2025` Edited by `admin` on `Tue Apr 01 23:43:08 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	3OX1DBR75G
Record Status	`FAILED`
Record Version

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Name

Type

Language

Immunoglobulin G1 [300-alanine], anti-(human CD73 antigen) (human-Mus musculus monoclonal TJ004309 ?1-chain), disulfide with human-Mus musculus monoclonal TJ004309 ?-chain, dimer

Preferred Name

English

ULILEDLIMAB

Official Name

English

uliledlimab [INN]

Common Name

English

ULILEDLIMAB [USAN]

Common Name

English

TJ-D5

Code

English

Uliledlimab [WHO-DD]

Common Name

English

TJ-004309

Code

English

Immunoglobulin G1-kappa, anti-[Homo sapiens NT5E (5'-nucleotidase ecto, 5' nucleotidase, NT5, eN, eNT NTE, CALJA, CD73)], monoclonal antibody; gamma1 heavy chain (1-450) [VH (Homo sapiens IGHV4-38-2*01 (87.6%) -(IGHD) -IGHJ6*01 (100%)) CDR-IMGT [9.7.13]

Common Name

English

TJ004309

Code

English

Code System Code Type Description

NCI_THESAURUS

C159168

Created by admin on Tue Apr 01 23:43:08 GMT 2025 , Edited by admin on Tue Apr 01 23:43:08 GMT 2025

PRIMARY

INN

11597

Created by admin on Tue Apr 01 23:43:08 GMT 2025 , Edited by admin on Tue Apr 01 23:43:08 GMT 2025

PRIMARY

INN

SMS_ID

300000032313

Created by admin on Tue Apr 01 23:43:08 GMT 2025 , Edited by admin on Tue Apr 01 23:43:08 GMT 2025

PRIMARY

CAS

2378407-27-1

Created by admin on Tue Apr 01 23:43:08 GMT 2025 , Edited by admin on Tue Apr 01 23:43:08 GMT 2025

PRIMARY

USAN

KL-99

Created by admin on Tue Apr 01 23:43:08 GMT 2025 , Edited by admin on Tue Apr 01 23:43:08 GMT 2025

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FDA UNII

3OX1DBR75G

Created by admin on Tue Apr 01 23:43:08 GMT 2025 , Edited by admin on Tue Apr 01 23:43:08 GMT 2025

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From	To
1_22	1_96
1_147	1_203
3_23	3_87
3_133	3_193
1_223	3_213
2_22	2_96
2_147	2_203
4_23	4_87
4_133	4_193
2_223	4_213
1_229	2_229
1_232	2_232
1_264	1_324
1_370	1_428
2_264	2_324
2_370	2_428

Related Record Type Details


					T8635M4C7O

5'-NUCLEOTIDASE

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					3OX1DBR75G

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_450] [2_450]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL