U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sun Dec 18 10:53:07 UTC 2022
Edited
by admin
on Sun Dec 18 10:53:07 UTC 2022
Protein Type ENZYME
Protein Sub Type MONOAMINE OXIDASE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
3OV8HVI592
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMINE OXIDASE (FLAVIN-CONTAINING) B
Common Name English
MOA-B
Common Name English
MAO-B
Common Name English
MONOAMINE OXIDASE TYPE B
Common Name English
MONOAMINE OXIDASE B
Common Name English
MAOB
Common Name English
MONOAMINE OXIDASE B (HUMAN)
Common Name English
Code System Code Type Description
UNIPROT
P27338
Created by admin on Sun Dec 18 10:53:09 UTC 2022 , Edited by admin on Sun Dec 18 10:53:09 UTC 2022
PRIMARY
WIKIPEDIA
MONOAMINE OXIDASE B
Created by admin on Sun Dec 18 10:53:09 UTC 2022 , Edited by admin on Sun Dec 18 10:53:09 UTC 2022
PRIMARY
FDA UNII
3OV8HVI592
Created by admin on Sun Dec 18 10:53:09 UTC 2022 , Edited by admin on Sun Dec 18 10:53:09 UTC 2022
PRIMARY
EC (ENZYME CLASS)
EC 1.4.3.4
Created by admin on Sun Dec 18 10:53:09 UTC 2022 , Edited by admin on Sun Dec 18 10:53:09 UTC 2022
PRIMARY
Related Record Type Details
RADIOLIGAND->TARGET
INHIBITOR -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
RADIOLIGAND->TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
IRREVERSIBLE INHIBITOR
INHIBITOR -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
SUBSTRATE->ENZYME
SUBSTRATE -> METABOLIC ENZYME
INHIBITOR -> TARGET
SUBSTRATE -> METABOLIC ENZYME
INHIBITOR -> TARGET
INHIBITOR -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
INHIBITOR -> TARGET
IRREVERSIBLE INHIBITOR
INHIBITOR -> TARGET
INHIBITOR -> METABOLIC ENZYME
MAO inhibition can lead to peripheral or central neurotransmitter accumulation, with potentially serious consequences. MAO inhibitors, when taken in combination with vasoconstrictors, such as pseudoephedrine, or high dietary tyramine can cause sudden blood pressure elevations that may lead to hypertensive crises. Combination with serotonergic agents may lead to rare, but potentially life-threatening, serotonin syndrome
IC50
RADIOLIGAND->TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL