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Details

Stereochemistry ACHIRAL
Molecular Formula C8H12NO5PS2
Molecular Weight 297.288
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CYTHIOATE

SMILES

COP(=S)(OC)OC1=CC=C(C=C1)S(N)(=O)=O

InChI

InChIKey=BSBSDQUZDZXGFN-UHFFFAOYSA-N
InChI=1S/C8H12NO5PS2/c1-12-15(16,13-2)14-7-3-5-8(6-4-7)17(9,10)11/h3-6H,1-2H3,(H2,9,10,11)

HIDE SMILES / InChI
Molecular Formula C8H12NO5PS2
Molecular Weight 297.288
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Cythioate is an organothiophosphate chemical used as an insecticide and anthelmintic. Cythioate is a cholinesterase inhibitor. Marketed under the trade names Cyflee and Proban, Cythioate is indicated for the control of ticks, fleas, and demodectic mange in dogs, and fleas in cats.

Originator

American Cyanamid
37

Approval Year

Unknown
139,594

Targets

Primary TargetPharmacologyConditionPotency
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)
1
Inhibitor
8,297

Conditions

ConditionModalityTargetsHighest PhaseProduct
Demodicosis
1
 Curative
Approved
8,429
Proban

PubMed

Patents

JP2008509189A
188
US4781920
1

Sample Use Guides

In Vivo Use Guide
Dogs: 15 milligrams cythioate per 10 pounds of body weight every third day or twice a week.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
3OOH7Q4333
Record Status Validated (UNII)
Record Version
NIH
NCATS
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