Details
| Stereochemistry | MIXED |
| Molecular Formula | C7H16FO2P |
| Molecular Weight | 182.1729 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(OP(C)(F)=O)C(C)(C)C
InChI
InChIKey=GRXKLBBBQUKJJZ-UHFFFAOYSA-N
InChI=1S/C7H16FO2P/c1-6(7(2,3)4)10-11(5,8)9/h6H,1-5H3
| Molecular Formula | C7H16FO2P |
| Molecular Weight | 182.1729 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| A guinea pig hippocampal slice model of organophosphate-induced seizure activity. | 2004-08 |
|
| Effect of organophosphorus hydrolysing enzymes on obidoxime-induced reactivation of organophosphate-inhibited human acetylcholinesterase. | 2004-06 |
|
| A fluorogenic substrate for detection of organophosphatase activity. | 2004-04-01 |
|
| Periodic orbit analysis reveals subtle effects of atropine on epileptiform activity in the guinea-pig hippocampal slice. | 2004-03-11 |
|
| Organophosphate-induced convulsions and prevention of neuropathological damages. | 2004-03-01 |
|
| Inhalational exposure to nerve agents. | 2004-03 |
|
| The application of the fluoride reactivation process to the detection of sarin and soman nerve agent exposures in biological samples. | 2004-02 |
|
| Function of plasma and microsomal enzymes in soman toxicity. | 2004-02 |
|
| Effects of fosphenytoin on nerve agent-induced status epilepticus. | 2004-02 |
|
| Antagonism of anticholinesterase (DFP) toxicity by donepezil plus scopolamine: a preliminary study. | 2004-02 |
|
| Estimation of the upper limit of human butyrylcholinesterase dose required for protection against organophosphates toxicity: a mathematically based toxicokinetic model. | 2004-02 |
|
| Cognitive side effects in rats caused by pharmacological agents used to prevent soman-induced lethality. | 2004-01-12 |
|
| The effect of fluoride on the scavenging of organophosphates by human butyrylcholinesterase in buffer solutions and human plasma. | 2004-01-01 |
|
| Chemical warfare agents: their past and continuing threat and evolving therapies. Part I of II. | 2003-12-16 |
|
| Early changes in MAP2 protein in the rat hippocampus following soman intoxication. | 2003-11 |
|
| Central neuro-inflammatory gene response following soman exposure in the rat. | 2003-10-09 |
|
| DNA fragmentation in leukocytes following subacute low-dose nerve agent exposure. | 2003-10 |
|
| A comparison of the decontamination efficacy of foam-making blends based on cationic and nonionic tensides against organophosphorus compounds determined in vitro and in vivo. | 2003-09 |
|
| Anticholinergic and antiglutamatergic agents protect against soman-induced brain damage and cognitive dysfunction. | 2003-09 |
|
| Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase. | 2003-08-01 |
|
| Organophosphate nerve agent toxicity in Hydra attenuata. | 2003-08 |
|
| Effects of pretreatment with 8018 on the toxicokinetics of soman in rabbits and distribution in mice. | 2003-07-11 |
|
| Partial adenosine A(1) receptor agonists inhibit sarin-induced epileptiform activity in the hippocampal slice. | 2003-06-20 |
|
| Putative role of proteolysis and inflammatory response in the toxicity of nerve and blister chemical warfare agents: implications for multi-threat medical countermeasures. | 2003-06-10 |
|
| Neuroprotective effects of currently used antidotes in tabun-poisoned rats. | 2003-06 |
|
| Pharmacological agents, hippocampal EEG, and anticonvulsant effects on soman-induced seizures in rats. | 2003-06 |
|
| Human carboxylesterase 1: from drug metabolism to drug discovery. | 2003-06 |
|
| Gulf war syndrome: narrowing the possibilities. | 2003-05 |
|
| Take your pyridostigmine: that's an (ethical?) order! | 2003-05 |
|
| Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme. | 2003-05 |
|
| Control of nerve agent-induced seizures is critical for neuroprotection and survival. | 2003-04-15 |
|
| Hydrolytic properties of per (3,6-anhydro, 2-O-carboxymethyl) alpha cyclodextrin complexes of Ce (III) and Eu (III): application to soman (GD) degradation. | 2003-04 |
|
| Field verification of Test-mate ChE. | 2003-04 |
|
| Clinical trials. New rule triggers debate over best way to test drugs. | 2003-03-14 |
|
| Effects of pretreatment with verapamil on the toxicokinetics of soman in rabbits and distribution in mouse brain and diaphragm. | 2003-03-03 |
|
| The effect of acetylcholinesterase-inhibition on depolarization-induced GABA release from rat striatal slices. | 2003-03-03 |
|
| Assessment of a combination of physostigmine and scopolamine as pretreatment against the behavioural effects of organophosphates in the common marmoset (Callithrix jacchus). | 2003-03 |
|
| Pharmacokinetics of intramuscularly administered biperiden in guinea pigs challenged with soman. | 2003-02 |
|
| Low concentrations of pyridostigmine prevent soman-induced inhibition of GABAergic transmission in the central nervous system: involvement of muscarinic receptors. | 2003-01 |
|
| The ratio of serum paraoxonase/arylesterase activity using an improved assay for arylesterase activity to discriminate PON1(R192) from PON1(Q192). | 2003 |
|
| Inhalation apparatus for generating sarin and soman toxic vapors. | 2003 |
|
| A comparison of the neuroprotective efficacy of pharmacological pretreatment and antidotal treatment in soman-poisoned rats. | 2003 |
|
| Nimodipine affects the microcirculation and modulates the vascular effects of acetylcholinesterase inhibition. | 2003 |
|
| Alterations in brain glutathione homeostasis induced by the nerve gas soman. | 2003 |
|
| Measurements of chemical warfare agent degradation products using an electrophoresis microchip with contactless conductivity detector. | 2002-12-01 |
|
| Vesicants and nerve agents in chemical warfare. Decontamination and treatment strategies for a changed world. | 2002-10 |
|
| A review of nerve agent exposure for the critical care physician. | 2002-10 |
|
| Physostigmine and hyoscine improves protection against the lethal and incapacitating effects of nerve agent poisoning in the guinea-pig. | 2002-09 |
|
| [Scientific principles of sanitary and hygienic basis of chemical weapons demolishment]. | 2002 |
|
| Review of oximes in the antidotal treatment of poisoning by organophosphorus nerve agents. | 2002 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:56:53 GMT 2025
by
admin
on
Mon Mar 31 21:56:53 GMT 2025
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| Record UNII |
3OF3WXB67Q
|
| Record Status |
Validated (UNII)
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| Record Version |
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6764
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DTXSID2031906
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Soman
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96-64-0
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m10109
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admin on Mon Mar 31 21:56:53 GMT 2025 , Edited by admin on Mon Mar 31 21:56:53 GMT 2025
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PRIMARY | Merck Index | ||
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3OF3WXB67Q
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7305
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|---|---|---|---|---|
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