Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C11H11N4O3S.Na.H2O |
| Molecular Weight | 320.3 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.[Na+].COC1=NC=NC([N-]S(=O)(=O)C2=CC=C(N)C=C2)=C1
InChI
InChIKey=FCRXFGJGZLBJRP-UHFFFAOYSA-N
InChI=1S/C11H11N4O3S.Na.H2O/c1-18-11-6-10(13-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9;;/h2-7H,12H2,1H3;;1H2/q-1;+1;
| Molecular Formula | C11H12N4O3S |
| Molecular Weight | 280.303 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | HO |
| Molecular Weight | 17.0073 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionCurator's Comment: description was created based on several sources, including
https://www.goldbio.com/product/3383/sulfamonomethoxine
http://ft.chqmarket.com/en/1059-compound-sulfamonomethoxine-sodium-injection-baclean.html
Curator's Comment: description was created based on several sources, including
https://www.goldbio.com/product/3383/sulfamonomethoxine
http://ft.chqmarket.com/en/1059-compound-sulfamonomethoxine-sodium-injection-baclean.html
Sulfamonomethoxine is a long-acting sulfonamide antibiotic. It is active against Streptococcus spp. (Including Streptococcus pneumoniae, Enterococcus spp.), Staphylococcus spp., Escherichia coli, Shigella spp., some strains of Proteus spp., Neisseria gonorrhoeae, Neisseria meningitides. Sulfamonomethoxine also active against Chlamydia spp., Toxoplasma gondii, Plasmodium. Rapidly absorbed from the gastrointestinal tract, it penetrates the BBB. The relatively low toxicity. Sulfamonomethoxine is a competitive inhibitor of dihydropteroate synthetase used to block the synthesis of folic acid. By preventing the production of folate in bacteria, the sulfonamide antibiotics ultimately suppress bacterial DNA replication.
Approval Year
Sample Use Guides
adult: 1 tablet per day (500 mg- 1 g per day)
children: 25 mg/kg per day at the first day, then 12,5 mg/kg per day
Route of Administration:
Oral
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 05:52:52 GMT 2023
by
admin
on
Sat Dec 16 05:52:52 GMT 2023
|
| Record UNII |
3O63314C1L
|
| Record Status |
Validated (UNII)
|
| Record Version |
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-
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23724826
Created by
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3O63314C1L
Created by
admin on Sat Dec 16 05:52:52 GMT 2023 , Edited by admin on Sat Dec 16 05:52:52 GMT 2023
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300000033591
Created by
admin on Sat Dec 16 05:52:52 GMT 2023 , Edited by admin on Sat Dec 16 05:52:52 GMT 2023
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| Related Record | Type | Details | ||
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ANHYDROUS->SOLVATE | |||
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PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |