Approval Year
| Substance Class |
Structurally Diverse
Created
by
admin
on
Edited
Sat Dec 16 15:40:11 UTC 2023
by
admin
on
Sat Dec 16 15:40:11 UTC 2023
|
| Source Materials Class | ORGANISM |
| Source Materials Type | ALLOGENIC HUMAN |
| Source Materials State | LIVE GENETICALLY MODIFIED |
| Source Materials Parent | |
| Part | PLURIPOTENT |
| Fraction Name | natural killer cells |
| Record UNII |
3NBZ936ONT
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
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Code | English | ||
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Code | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
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3NBZ936ONT
Created by
admin on Sat Dec 16 15:40:11 UTC 2023 , Edited by admin on Sat Dec 16 15:40:11 UTC 2023
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PRIMARY | |||
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C164140
Created by
admin on Sat Dec 16 15:40:11 UTC 2023 , Edited by admin on Sat Dec 16 15:40:11 UTC 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
direct cytotoxicity through the targeted release of perforins and granzymes; cytokine secretion which can activate and recruit an endogenous adaptive immune response; via antibody-dependent cellular cytotoxicity (ADCC), which occurs when an antibody binds to a tumor cell and the antibody’s Fc region binds to the CD16 receptor on NK cells, triggering a cytotoxic response towards the tumor cell
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Agent Modifications
| Modification Process | Modification Role | Modification Type | Amount | Fragment Name | Fragment ID |
|---|---|---|---|---|---|
| CD34 enrichment | IMMUNOLOGICAL | ||||
| TRANSESTERIFICATION | LENTIVIRAL TRANSFECTION | UNSPECIFIED SUBSTANCE | f5636d93 |