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Details

Stereochemistry ACHIRAL
Molecular Formula C19H36NO2
Molecular Weight 310.4946
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 4
E/Z Centers 0
Charge 1

SHOW SMILES / InChI
Structure of SINTROPIUM

SMILES

CCCC(CCC)C(=O)O[C@@H]1C[C@@H]2CC[C@H](C1)[N@+]2(C)C(C)C

InChI

InChIKey=NCCCVLZKNQKUCJ-GKUGNITKSA-N
InChI=1S/C19H36NO2/c1-6-8-15(9-7-2)19(21)22-18-12-16-10-11-17(13-18)20(16,5)14(3)4/h14-18H,6-13H2,1-5H3/q+1/t16-,17+,18+,20?

HIDE SMILES / InChI

Molecular Formula C19H36NO2
Molecular Weight 310.4946
Charge 1
Count
Stereochemistry EPIMERIC
Additional Stereochemistry No
Defined Stereocenters 3 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Sintropium [VAL 480] is a gastrointestinal, biliary and urinary spasmolytic agent that was under development with Valeas in Italy. It is a muscarinic receptor antagonist. Sintropium bromide has a prompt anticholinergic action and for this reason may be used in the treatment of painful conditions of the bile, gastro-enteric and renal tracts, and also during the course of endoscopic examinations.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Clinical evaluation of a new spasmolytic: sintropium bromide (VAL 480) in spastic states of the upper and lower urinary tract].
1986 Jul-Sep
[The use of sintropium bromide, a new spasmolytic, in obstetrics and gynecology].
1986 Nov
[Sintropium bromide (VAL 480): a new spasmolytic agent in general surgery].
1986 Oct 15
Patents

Sample Use Guides

LD50 i.p. in male mice: 77 mg/kg
Route of Administration: Intraperitoneal
Substance Class Chemical
Created
by admin
on Sat Dec 16 02:55:44 GMT 2023
Edited
by admin
on Sat Dec 16 02:55:44 GMT 2023
Record UNII
3N9B1PL5QG
Record Status Validated (UNII)
Record Version
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Name Type Language
SINTROPIUM
Common Name English
SINTROPIUM CATION
Common Name English
SINTROPIUM ION
Common Name English
8-AZONIABICYCLO(3.2.1)OCTANE, 8-METHYL-8-(1-METHYLETHYL)-3-((1-OXO-2-PROPYLPENTYL)OXY)-, (3-ENDO,8-SYN)-
Common Name English
Code System Code Type Description
PUBCHEM
174170
Created by admin on Sat Dec 16 02:55:44 GMT 2023 , Edited by admin on Sat Dec 16 02:55:44 GMT 2023
PRIMARY
CAS
768313-41-3
Created by admin on Sat Dec 16 02:55:44 GMT 2023 , Edited by admin on Sat Dec 16 02:55:44 GMT 2023
PRIMARY
FDA UNII
3N9B1PL5QG
Created by admin on Sat Dec 16 02:55:44 GMT 2023 , Edited by admin on Sat Dec 16 02:55:44 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY